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July 30, 2012
This illustration depicts the nanolipogel, a new drug transport technology developed at Yale University with National Science Foundation (NSF) support, administering its immunotherapy cargo. The light-blue spheres within the blood vessels and the cutaway sphere in the foreground are the nanolipogels (NLGs). As the NLGs break down, they release IL-2 (the green specks), which helps recruit and activate a body's immune response (the purple, sphere-like cells). The tiny, bright blue spheres are the additional treatment, a cancer drug that inhibits TGF-beta (one of the cancer's defense chemicals). The research was led by Tarek Fahmy, a Yale University engineering professor and an NSF Faculty Early Career Development (CAREER) program awardee. Credit: Nicolle Rager Fuller, NSF