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O395 wt Cholera Wild Type
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O395 wt Cholera Wild Type

March 6, 2013
Transmission electron microsope image of Vibrio choleraethat has been negatively stained. Vibrio choleraeis the bacteria responsible for the gastroinestinal disease cholera. In order to get the disease cholera, the bacteria must be able to colonize in the small intestine and a critical factor necessary for this colonization is the toxin-co-regulated pilus(TCP). 0395 is a wild type strain, showing the normal bundling of toxin-co-regulated pilus(TCP). Wild-type pili are clearly visible as 7 nm fibres that form bundles @ 0.2Ð0.3 µm wide and 3Ð6 µm long. For more information, see the journal article: T.J. Kirn, M.J. Lafferty, C.M.P Sandoe and R.K. Taylor, 2000, "Delineation of pilin domains required for bacterial association into microcolonies and intestinal colonization", Molecular Microbiology, Vol. 35(4):896-910 JEOL TEM 100CX Credit: Tom Kirn, Ron Taylor, Louisa Howard


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