Last updated on April 21, 2014 at 5:21 EDT

RIFM Innovative Model Calculates Inhalation Exposure To Fragrance Materials

May 3, 2012

RIFM 2-Box Indoor Air Dispersion Model Is An Alternative Method To Calculate Inhalation Exposure To Fragrance

WOODCLIFF LAKE, N.J., May 3, 2012 /PRNewswire-USNewswire/ –The Research Institute for Fragrance Materials, Inc. (RIFM) is beta testing its innovative 2-Box Indoor Air Dispersion Model software, an alternative method for assessing inhalation exposure to fragrance materials. RIFM Database subscribers can download the model for individual use by selecting “Tools and Models” from the RIFM Database home page and then selecting the model for download. The RIFM Database can be accessed from the Database section of the RIFM Science area on the web site at www.rifm.org. A webinar will be held on May 31st at 10 am (EDT) to give detailed instruction on how to use the Model.

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The 2-Box Indoor Air Dispersion Model is a computational, indoor environment, air exposure model that characterizes the movement of a single chemical inside two connected, enclosed rooms. The model allows the user to determine air concentrations, over time, to assess potential inhalation exposure for different air care products under defined conditions of consumer use. The 2-Box Air Dispersion Model has been instrumental to the Systemic Quantitative Risk Assessment (QRA) Task Force for the inhalation aspect of their analysis of exposure from dermal, oral, and inhalation routes, and for aggregate exposure.

The 2-Box Indoor Air Dispersion Model software functions independently but can be used in conjunction with the Multiple Path Particle Deposition (MPPD) Model which will be available soon. The MPPD Model will calculate material deposition in the upper and lower respiratory tract. Dr. Madhuri Singal, Manager, Respiratory Science at RIFM said, “We are proud to unveil the RIFM 2-Box Air Dispersion Model. A milestone for the Respiratory Science Program, this computational model is a great alternative risk assessment tool that will provide useful information for everyday inhalation exposure calculations. It is an important complement to the MPPD Model, coming soon.”

Please send your feedback on the 2-Box Indoor Air Dispersion Model to Danielle Vitale, Respiratory Specialist, dvitale@rifm.org. It will help RIFM to refine and further enhance the software.

For nonsubscriber access, contact Ms. Christen Sachse-Vasquez, Director, Technical Information and Services,

RIFM is the international scientific authority for the safe use of fragrance materials. RIFM generates, evaluates and distributes scientific data on the safety assessment of fragrance raw materials found in personal and household care products. Through extensive research, testing and constant monitoring of all scientific literature available, RIFM maintains its Database as the most comprehensive source worldwide of physical-chemical, toxicological and eco-toxicological data associated with known fragrance and flavor materials. All of RIFM’s scientific findings are evaluated by an independent Expert Panel–an international group of dermatologists, pathologists, toxicologists, reproduction, respiratory and environmental scientists. The Expert Panel evaluates the safety of fragrance ingredients under conditions of intended use and publishes their results in peer-reviewed scientific journals. The decisions of the Expert Panel regarding restrictions of use are also published in the IFRA Standards. For more information about RIFM and its activities, visit www.rifm.org or e-mail rifm@rifm.org.

Contact: Marie Gartshore, Communications Manager
e-mail: mgartshore@rifm.org
tel: 201.689.8089, ext. 111

SOURCE Research Institute for Fragrance Materials, Inc.

Source: PR Newswire