July 1, 2008

Spire Corporation to Present at Collins Stewart’s 4th Annual Growth Conference

Spire Corporation (Nasdaq: SPIR), a global solar company providing turnkey solar factories and capital equipment to manufacture photovoltaic cells and modules worldwide, today announced that members of its executive management will be presenting at Collins Stewart's 4th Annual Growth Conference. The conference will be held from July 8 to 10, 2008 at The Mandarin Oriental Hotel in New York City, New York. Spire will present at 2:30 p.m. (ET) on Tuesday, July 8, 2008.

At the conference, Mark C. Little, Director of Investor Relations and Chief Executive Officer of Spire Biomedical and Dr. Christian Dufresne, Chief Financial Officer and Treasurer will discuss Spire Corporation's business strategy and review the Company's recent accomplishments. The presentation will be broadcast live over the Internet. Those interested in listening to the live or archived webcast can log on to the "Investors" section of Spire Corporation's website, www.spirecorp.com.

About Spire Corporation

Spire Corporation is a global solar company providing turnkey production lines and capital equipment to manufacture photovoltaic cells and modules worldwide. Spire Semiconductor provides processing technology for Spire's silicon solar cell manufacturing lines, and produces and sells custom gallium arsenide cells for solar concentrator systems.

For corporate or product information, contact Spire Corporation, "The Turnkey Solar Factory Company," at 781-275-6000, or visit www.spirecorp.com.

Certain matters described in this news release may be forward-looking statements subject to risks and uncertainties that could cause actual results to differ materially from those indicated in the forward-looking statements. Such risks and uncertainties include, but are not limited to, the risk of dependence on market growth, competition and dependence on government agencies and other third parties for funding contract research and services, as well as other factors described in the Company's Form 10-K and other periodic reports filed with the Securities and Exchange Commission.