August 19, 2009
Lilly pulls plug on osteoporosis drug
The Indiana pharmaceutical firm Eli Lilly has announced a potential treatment for osteoporosis had disappointing results in a five-year clinical trial.
Lilly officials said Tuesday it will not apply to federal regulators for approval of arzoxifene, the Indianapolis Star reported.
Evista, the company's current osteoporosis drug, goes off-patent in 2014, and arzoxifene had been touted as a replacement.
Officials said the clinical trial showed arzoxifene reduces the risk of spine fractures and of breast cancer in women who have been through menopause. But in a number of other areas, including fractures in other locations, the drug performed no better than a placebo.