Last updated on April 23, 2014 at 21:24 EDT

Economist Intelligence Unit Report Calls for Global Policy Innovation to Tackle the ‘Silent Pandemic’ That is Hepatitis C

January 15, 2013

LONDON, January 15, 2013 /PRNewswire/ –

– Experts recommend comprehensive approach to combat global health issue -

A new Economist Intelligence Unit (EIU) report titled The Silent Pandemic: Tackling
Hepatitis C with Policy Innovation, made possible as a result of an educational grant from
Janssen Pharmaceutica NV and published today, highlights the urgent need for countries
around the world to develop strategies to tackle head-on the growing social and economic
issues associated with Hepatitis C (HCV).[1]

To view the Multimedia News Release, please click:


While the total number of infected individuals is unknown due to a lack of available
data, the World Health Organization (WHO) estimates that approximately 150 million people
globally are currently living with the blood-borne infectious disease, HCV.[2] Of these,
up to two thirds will develop chronic liver disease and one in five will develop
cirrhosis.[2] HCV is also the leading cause of liver transplantation worldwide[1] and in
the US the disease now accounts for more deaths than HIV.[1]

“The report highlights that worldwide, despite the significant burden of HCV,
governments have failed to get a grip on the scale and impact of the disease,” said
Charles Gore, President of The World Hepatitis Alliance. “In both developed and developing
countries, the true human and economic cost of HCV will continue to rise unless policy
makers confront this urgent public health issue now.”

Despite the devastating effects of HCV, the report states that it is now considered
preventable and with modern treatments, the majority of suffers can become clear of the
virus.[1] The report notes, however, that as few as 10% of patients are currently
receiving treatments and there is a large disparity in care across countries.[1] As a
result, the report calls for countries to take a “comprehensive approach,” which takes
into account local needs and resources available. This includes the following:[1]

        - Effective disease surveillance to create an accurate picture of the
          problem and ensure effective policies can be developed. The report claims that too few
          countries - developed or developing - have recently conducted the epidemiological
          studies necessary for good policy-making at a national, let alone a local, level.
          According to the EIU, 16 countries in the EU alone have epidemiological data that is
          either poor or non-existent.[1]
        - Better public awareness is needed to help remove the stigma associated with
          the disease and create better understanding of HCV.[1] A survey by the European Liver
          Patients Association found that only 20% of those diagnosed had heard of hepatitis B
          or C before being told they had it[1] (full survey results are available at:


        - Prevention measures to reduce high-risk behaviour and improve education on
          healthy lifestyle choices for those already infected. The report also calls for
          measures to prevent transmission via healthcare systems, which is the major route of
          transmission of HCV in developing countries.[1]
        - Innovative ways to reach out to patients to ensure those who need treatment
          receive it before irreversible conditions develop.[1]

“The report highlights that each country has different needs and resources; however,
we urge all those involved in the management of HCV and public health to help increase
awareness of the disease and look at the most effective ways of delivering effective
treatment to those most in need,” said Gaston Picchio, Global Hepatitis Disease Area
Leader, Janssen. “Janssen is committed to working with the HCV community and will continue
to engage with healthcare professionals, government officials and patient advocates around
the world to support their efforts to reduce the individual and societal burden of this
devastating disease.”

A full copy of the EIU report and supporting materials, including an info-graphic, is
available at: http://www.janssen-emea.com/The-silent-pandemic

About HCV

Hepatitis C (HCV) is a blood-borne infectious disease that affects the liver.[3],[4]
With an estimated 150 million people infected worldwide,[2] and three to four million
people newly infected each year, HCV puts a significant burden on patients and society.[5]
Estimations indicate that HCV caused more than 86,000 deaths and 1.2 million
disability-adjusted life-years (DALYs) in the WHO European region in 2002 (latest data
available).[6] Chronic infection with HCV can lead to liver cancer and other serious and
fatal liver diseases.[7] About one-quarter of the liver transplantations performed in 25
European countries in 2004 were attributable to HCV (latest data available).[6]

About Janssen

At Janssen, we are dedicated to addressing and solving some of the most important
unmet medical needs of our time in infectious diseases and vaccines, oncology, immunology,
neuroscience, and cardiovascular and metabolic diseases. Driven by our commitment to
patients, we develop innovative products, services and healthcare solutions to help people
throughout the world. Please visit http://www.janssen.com for more information.


        1) Economist Intelligence Unit. 2012. The Silent Pandemic: Tackling
          Hepatitis C with Policy Innovation. Available at:


        2) World Health Organization. Hepatitis C Fact Sheet. Available at:
          http://www.who.int/mediacentre/factsheets/fs164/en/index.html (last accessed
          December 2012)
        3) Simin, M et al. 2007. Cochrane systematic review: pegylated interferon plus
          ribavirin vs. interferon plus ribavirin for chronic hepatitis C. Alimentary
          Pharmacology & Therapeutics 25 (10): 1153-62.
        4) Centres for Disease Control and Prevention. Hepatitis C FAQs. Available from:
          http://www.cdc.gov/hepatitis/C/cFAQ.htm#transmission (last accessed December 2012)
        5) WHO. State of the art of vaccine research and development. Viral Cancers.
          Available from: http://www.who.int/vaccine_research/documents/Viral_Cancers.pdf
          (last accessed December 2012)
        6) Muehlberger, N et al. 2009. HCV-related burden of disease in Europe: a
          systematic assessment of incidence, prevalence, morbidity, and mortality. BMC Public
          Health 9 (34): 1-14.
        7) Lang K & Weiner DB. 2008. Immunotherapy for HCV infection: next steps. Expert
          Review of Vaccines 7 (7): 915-923.



SOURCE Janssen

Source: PR Newswire