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The World Market for Cancer Diagnostics, 5th Edition: Precision and Personalized Testing Arrives

May 5, 2014

LONDON, May 5, 2014 /PRNewswire/ — Reportbuyer.com has added a new market research report:

The World Market for Cancer Diagnostics, 5th Edition: Precision and Personalized Testing Arrives

http://www.reportbuyer.com/pharma_healthcare/diagnostics/world_market_cancer_diagnostics_5th_edition_precision_personalized_testing_arrives.html

Cancer testing is maturing from personalized medicine to precision medicine, where protein and molecular biomarkers are essential for precise diagnosis, therapy selection, therapy monitoring and early detection of cancer recurrence. The market for cancer testing are comprehensively covered in Kalorama Information’s Worldwide Market for Cancer Diagnostics, 5th. Edition.

This report, authored by Kalorama Diagnostic Analyst Shara Rosen, contains detailed market data on the following IVD segments for their use in cancer diagnostics:

– Histology/Cytology
– Immunoassays
– Flow Cytometry
– Rapid Tests
– Molecular Assays
– Tissue Arrays
– Circulating Tumor Cells
– Pharmacodiagnostics, Molecular

Given the unfortunate statistics of cancer in the developed world, innovation is a must. Growth rates in cancer testing tends to be higher than in other IVD fields. Diagnostic tests for effective cancer screening are obviously needed more than ever. As this report goes to print a number of significant developments are taking place in cancer follow up.

– New imaging modalities and digital analysis of x-ray mammograms are looking to improve the accuracy of breast cancer screening. These same imaging techniques are being used to screen patients for the metastasis of cancer from the primary site.
– Lab testing for new cancer biomarkers – hormone, receptor and protein assays – improve the detection of cancer in patients that present with symptoms. These are now available in multiplexed tests that make better use of tissue samples.
– With developments in the analysis of circulating cancer cells and cell free DNA in peripheral blood they are poised to help in the screening of high risk individuals.
– Improved immunohistochemical stains and in situ hybridization make detection of cancer cells in biopsied tissue more effective. The use next generation analysis of individual tumor cells including sequencing, mass spectrometry and PCR further enhance cancer testing in tissues.
– Bioinformatic analysis of gene and protein patterns detected in tumor cells and peripheral blood is proving to be a big breakthrough in cancer diagnosis. The technology has pinpointed gene and protein targets that will make up the next generation of cancer tumor marker panels.
– The next big advances are related to tests based on the detection of circulating nucleic acid molecules and RNA and DNA methylation patterns.

Complete Market and Trend Analysis

Kalorama Information reports are always based on primary research of the market with particular attention to important market trends that are more important to understand than today’s numbers. Shara Rosen not only defines the marketplace and provides market numbers, but her report also examines trends that are driving cancer testing now and determining where it will go in the future.

Some of the trends examined in this report include:

– Commercializing Next Generation Cancer Tests
– Clinical Molecular Test Reimbursement Coding In The U.S.
– Regulatory Requirements of Cancer Tests
– Gene Patents and Test Commercialization
– Miniaturization and Multiplexed Assays
– The Emergence Of Non-Invasive Tools
– Bioinformatics – Data To Information
– Digital PCR, Mass Spectrometry, Next-Generation Sequencing
– The Role of In Vivo Cellular and Molecular Imaging and Analyst Conclusions, Strategy Implications and Unmet Market Needs

CHAPTER ONE: EXECUTIVE SUMMARY
Introduction
Scope and Methodology
Size and Growth of the Market

Test Segments
Geographic Distribution
Market Trends

CHAPTER TWO: INTRODUCTION
Background
Cancer – Diagnosis And Therapy Management
Point of View
CHAPTER THREE: MARKET ISSUES IN THE COMMERCIALIZATION OF CANCER DIAGNOSTICS
Background
Demographics of cancer, A Global Phenomenon
Cancer World Market Estimate
Cancer in the World – Screening and Government Supported Programs

United States
Canada
Europe
China
India
Africa


Commercializing Next Generation Cancer Tests
Clinical Molecular Test Reimbursement Coding In The U.S.

Test Services – Route For Cancer Innovation


Regulatory Requirements of Cancer Tests
Gene Patents and Test Commercialization
Impact of Companion Test Development
The Physician’s Role in Test Acceptance

CHAPTER FOUR: TECHNOLOGICAL TRENDS THAT ENABLE THE FUTURE OF CANCER DIAGNOSTICS
Background
Biomarkers: Issues in Research to Clinic
Miniaturization and Multiplexed Assays
The Emergence Of Non-Invasive Tools
Bioinformatics – Data To Information
New Technologies Applied To Cancer Diagnostics

Overview
Digital PCR
Mass Spectrometry
Chromosome Analysis
Next-Generation Sequencing
Sample Preparation and System Automation


The Role of In Vivo Cellular and Molecular Imaging

CHAPTER FIVE: MARKET ANALYSIS – CANCER TESTING
The Market for Cancer Diagnostics
Major Vendors and Companies to Watch
Acquisitions, Alliances and Collaborations
Screening – The Debate Continues
Prospects for Decentralized Cancer Testing
Cancer Specific Tests

Breast Cancer
Colon Cancer
Lung Cancer
Ovarian Cancer
Pancreatic Cancer

CHAPTER SIX: CANCER TESTS IN CLINICAL CHEMISTRY
Selected Tissue Function Clinical Chemistry Tests
Major Players In Chemistry Analyzers and Reagents

CHAPTER SEVEN: IMMUNOASSAY CANCER TESTS
Role Of Immunoassays In Cancer Management

Selected Widely Used Tumor Markers


Lab-Based Assays
POC – rapid tests

Colon Cancer
Prostate Cancer
Bladder Cancer

CHAPTER EIGHT: TISSUE- AND CELL-BASED CANCER TESTS
Background
Market Overview

Pap Smear & HPV Testing
Tissue Microarrays
Cell Signaling Pathway Testing

CHAPTER NINE: MARKET ANALYSIS – CANCER TESTS IN FLOW CYTOMETRY
Market Size

Selected Flow Cytometry Innovations For Cancer Testing

CHAPTER TEN:MARKET ANALYSIS – CIRCULATING TUMOR CELLS IN CANCER DIAGNOSTICS
Market Size

Selected CTC Capture And Analysis Systems

CHAPTER ELEVEN: – CANCER MOLECULAR ASSAYS
Background

RNA – Ribonucleic Acid
Methylated Gene (meDNA) Patterns
Circulating Plasma DNA
Minimal Residual Disease

CHAPTER TWELVE: PERSONALIZED CANCER TESTING ADVANCES IN PRECISION
Background

Pharmacodiagnostic Histology
Therapeutic Drug Monitoring Immunoassays

CHAPTER THIRTEEN: CONCLUSIONS AND STRATEGIC IMPLICATIONS
Conclusions and Strategic Implications
Unmet Market Needs

CHAPTER FOURTEEN: COMPANY PROFILES: MAJOR IVD COMPANY CANCER TESTING
Abbott Diagnostics

Molecular Histology
Companion Tests
Molecular Diagnostics
Core Lab
Hematology


Alere

NMP22


Beckman Coulter Inc./Danaher

Core Lab
Immunoassays
Histology
Flow Cytometry


Becton, Dickinson and Company (BD)

Histology
Molecular
Flow Cytometry


bioMérieux Inc.
Bio-Rad Laboratories Inc.
Danaher Corporation

AB Sciex
Leica


GE Healthcare

Cell Imaging
Sequencing


Gen-Probe Inc.

HPV


Hologic, Inc.
IRIS International, Inc.
Novartis Diagnostics
Ortho Clinical Diagnostics
PerkinElmer, Inc.

CLIA Lab


QIAGEN N.V.

Histology


Roche Diagnostics

PCR
Companion Tests
Hematological Cancers
Core Lab


Siemens Healthcare Diagnostics

Histology


Sysmex Corporation

CHAPTER FIFTEEN: COMPANY PROFILES: CIRCULATING TUMOR CELLS SPECIALISTS
Abnova
ApoCell, Inc.
Biocept, Inc.
Clearbridge BioMedics
Cynvenio Biosystems, Inc.
Epic Sciences Inc.
Fluxion Biosciences, Inc.
Ikonisys, Inc.
NaturalNano, Inc.
On-Q-ity
ProKyma Technologies
RareCyte, Inc.
ScreenCell
Sony DADC Biosciences
Veridex, LLC
WaveSense LLC

CHAPTER SIXTEEN: COMPANY PROFILES: TISSUE AND CELL TEST SPECIALISTS
Advanced Cell Diagnostics
Amoy Diagnostics Co. Ltd.
Applied Spectral Imaging
Biocare Medical, LLC
Biodis Biotechnology
BioMarker Strategies
Biomoda Inc.
BioView Ltd.
Bruker Corporation
CCC Diagnostics, Inc.
Caliper Life Sciences
Celerus Diagnostics
Cernostics, Inc.
ChipDX, LLC
Circadian Technologies Limited
Cymogen Dx, LLC
Dako A/S
Immunohistochemistry
Companion Diagnostics
Diagnostic Biosystems (DBS)
DVS Sciences Inc.
DxTerity Diagnostics Inc.
Halo Healthcare Inc. (formerly NeoMatrix, LLC)
HistoRx, Inc.
Horizon Discovery Ltd
iKaryos Diagnostics
IncellDx, Inc.
Leica Biosystems
Metamark Genetics, Inc.
Nodality, Inc.
Norchip
Oxford Cancer Biomarkers
Philips Handheld Diagnostics
QuantuMDx
Theranostics Health Inc.
Ventana Medical Systems Inc.
CHAPTER SEVENTEEN: COMPANY PROFILES: CANCER PROTEIN MARKER SPECIALISTS
Arbor Vita Corporation
Axela Biosensors, Inc.
Binding Site (The)
BioCurex, Inc.
Biomerica Inc.
Cellmid Ltd.
Eutropics Pharmaceuticals
Fujirebio Diagnostics, Inc.
GeneTex
Gold Standard Diagnostics:
HealthLinx Limited
Immunomedics
MabCure Inc.
Matrix-Bio
Nano Discovery Inc.
Oncimmune USA LLC
OncoCyte Corp.
OncoHealth Corp
OPKO Health, Inc.
Polymedco Cancer Diagnostic Products, LLC
Proteomika S.L.
Radient Pharmaceuticals Corporation
Saladax Biomedical, Inc.
ScheBo-Biotech AG
Wako Diagnostics
CHAPTER EIGHTEEN: COMPANY PROFILES: MOLECULAR TEST SPECIALISTS
Abcodia
Adaptive Biotechnologies Corporation
Affymetrix, Inc.
Agilent Technologies Inc.
ArcticDx Inc.
Arrayit Diagnostics Inc.
Asuragen, Inc.
Autogenomics Inc.
Biocartis
Biodesix, Inc.
Cepheid
DiagnoCure
Diagnoplex SA
Enzo Biochem Inc.
Epigenomics AG
Falcon Genomics, Inc.
GeneCentric Diagnostics, Inc.
GeneNews Limited
Genetic Technologies Limited
Genomica S.A.U.
Illumina Inc.
Inform Genomics, Inc.
Ipsogen SA
Life Technologies
Med BioGene, Inc. (MBI)
MicroActive Project
MolecularMD Corporation
NanoString Technologies Inc.
Onconome, Inc
Orion Genomics
Oxford Gene Technology
Randox Laboratories Ltd.
RainDance Technologies, Inc.
Sequenom
Skyline Diagnostics B.V.
Soricimed Biopharma Inc. (formerly BioProspecting NB Inc.)
Transgenomic, Inc.
TrimGen Genetic Technology
TrovaGene, Inc.
VolitionRx Limited
CHAPTER NINETEEN: COMPANY PROFILES: CANCER TEST SERVICE PROVIDERS
20/20 GeneSystems, Inc.
Acupath Laboratories, Inc.
Advanced Laboratory Services Inc.
Aetna Innovation Labs
Agendia BV
Market Expansion
Product News
AltheaDx Diagnostics, Inc.
ARUP Laboratories
Atossa Genetics, Inc.
BC Cancer Agency
Beijing Genome Institute (BGI)
Bio-Reference Laboratories, Inc. (BRLI)
bioTheranostics
Bostwick Laboratories
Cancer Genetics, Inc.
Caris Life Sciences
Castle Biosciences Inc.
CBLPath
Chronix Biomedical
Clarient Inc.
CombiMatrix Molecular Diagnostics, Inc.
Complete Genomics
deCode genetics ehf
DiaTech Oncology
Everist Genomics Inc. (EGI)
Exact Sciences Corp.
Exosome Diagnostics
Foundation Medicine Inc.
GenoID Ltd.
Genomic Health, Inc.
Genoptix Medical Laboratory
Inostics GmbH
Insight Genetics
InterGenetics Inc.
Lab21 Limited
Laboratory Corporation of America Holdings (LabCorp)
Mayo Medical Laboratories
MDxHealth SA (formerly Oncomethylome Sciences)
Metabolistics Inc.
Mira Dx
MolecularMD Corp.
Myriad Genetics, Inc.
NeoGenomics, Inc.
Nuvera Biosciences, Inc.
NewGene
OncoPlex Diagnostics (formerly Expression Pathology Inc.)
OvaGene Oncology Inc.
Pacific Edge Diagnostics
Pathwork Diagnostics
Phenomenome Discoveries Inc.
Precision Therapeutics
Predictive Biosciences
Quest Diagnostics
Response Genetics, Inc.
RiboMed Biotechnologies, Inc.
Rosetta Genomics Ltd.
Sequenta, Inc. (formerly MLC Dx, Inc.)
Signal Genetics
Signature Diagnostics AG
Veracyte, Inc.
Vermillion Inc.
LIST OF EXHIBITS
CHAPTER ONE: EXECUTIVE SUMMARY
Table 1-1: Exchange Rate Fluctuations, 2009-2012
Table 1-2: Worldwide Market for Cancer In Vitro Diagnostics, 2012-2017
Figure 1-1: Growth In Cancer In Vitro Diagnostics Market, 2012-2017
Table 1-3: Worldwide Market for Histology/Cytology Cancer IVD, 2012-2017
Table 1-4: Worldwide Market for Immunoassays Cancer IVD, 2012-2017
Table 1-5: Worldwide Market for Flow Cytometry Cancer IVD, 2012-2017
Table 1-6: Worldwide Market for Rapid Tests Cancer IV, 2012-2017
Table 1-7: Worldwide Market for Molecular Assays Cancer IVD, 2012-2017
Table 1-8: Worldwide Market for Tissue Arrays Cancer IVD, 2012-2017
Table 1-9: Worldwide Market for Circulating Tumor Cells Cancer IVD, 2012-2017
Table 1-10: Worldwide Market for Molecular Pharmacodiagnostics Cancer IVD, 2012-2017
CHAPTER TWO: INTRODUCTION
Table 2-1: Selected Test Gene Panel Targets (ALK, BRAF, C-Kit, EFGR, KRAS, P53, PIK3CA)
CHAPTER THREE: MARKET ISSUES IN THE COMMERCIALIZATION OF CANCER DIAGNOSTICS
Table 3-1: Cancer Incidence, Worldwide, By Cancer Type In 2008
Figure 3-1: World Cancer Test Sales, Percentage by Region (N. America, EU, Japan, ROW)
Table 3-2: World Cancer Test Market by Region (N. America, EU, Japan, ROW), 2007-2012
Table 3-3: Cancer Death Rates, by Region (Africa, Americas, Europe, Southeast Asia, Western Pacific, China, East Mediterranean, India), 2008
Table 3-4: Selected Cancer Company Lab Service Expansions
Table 3-5: Revenues For A Selection Of Molecular Test Service Labs, Worldwide, 2012, $ Million (Estimated)
Table 3-6: Selected Hospital Cancer Test Services
Table 3-7: Selected IVD and Pharmaceutical Company Collaborations
CHAPTER FOUR: TECHNOLOGICAL TRENDS THAT ENABLE THE FUTURE OF CANCER DIAGNOSTICS
Table 4-1: Selected Multiplexed Cancer Test And Service Innovations
Table 4-2: Selected Non-Invasive Cancer Test Innovations
Table 4-3: Selected Information Technology Innovations In Molecular Testing
Table 4-4: Selected App Products
Table 4-5: Selected Cancer Tests using Mass Spectrometry
Table 4-6: Selected Companies Involved In Chromosomal Analysis Of Cancer Cells
Table 4-7: Selected Chromosome-Based Cancer Tests And Services
Table 4-8: Sequencing Platforms Available
Table 4-9: Selected Sequencing-Based Tests And Test Services
Table 4-10: Selected Sample Preparation Systems for Sequencing Tests
Table 4-11: Selected Nucleic Acid Sample Preparation Products
MARKET OVERVIEW – MARKET ANALYSIS
Table 5-1: Worldwide Market for Selected Cancer In Vitro Diagnostics (Histology/Cytology, Immunoassays, Flow Cytometry, Rapid Tests, Molecular Assays, Tissue Arrays, CTCs, Pharmacodiagnostics, Circulating Plasma DNA), 2012-2017
Table 5-2: Revenues of Selected Cancer Testing Companies
Table 5-3: Cancer Diagnostics and the Top Tier of IVD Companies
Table 5-4: Selected Acquisitions, Mergers And New Cancer Test Investments
Table 5-5: Selected Cancer Test Collaborations
Table 5-6: Selected Cancer Test Distribution Agreements
Table 5-7: Selected Cancer Test Licensing Agreements
Table 5-8: Selected POL-appropriate Cancer Test Systems
CHAPTER SIX: CANCER TESTS IN CLINICAL CHEMISTRY
Table 6-1: Selected Tissue Function Clinical Chemistry Tests
Table 6-2: Major Players For Clinical Chemistry Analyzers And Reagents
CHAPTER SEVEN: IMMUNOASSAY CANCER TESTS
Table 7-1: Selected Widely Used Tumor Markers
Table 7-2: Selected Cancer Immunoassay Technology Innovations
Table 7-4: Cancer Immunoassay Sales, Lab-based (PSA, CEA, CA 125, AFP, Others), 2012-2017
Table 7-5: Rapid Cancer Test Sales by Test Category (FOB, PSA, NMP22, Other) Worldwide 2012-2017
CHAPTER EIGHT: TISSUE- AND CELL-BASED CANCER TESTS
Table 8-1: Selected Histology Test Services
Table 8-2: Selected Innovations In Tissue-Based Cancer Tests
Table 8-3: Worldwide Histology/Cytology Sales (Pap, in situ hybridization, immunohistochemistry, HPV, Tissue Microarrays), 2012-2017
Table 8-4: Revenues of the Major Histology Companies, 2009-2012
Table 8-5: Selected Major Protein And Molecular Markers
Table 8-6: Selected Technology Innovations In Cancer Testing
Table 8-8: Selected HPV Test Innovations
Table 8-9: Selected Tissue Microarray Products
Table 8-10: Selected Live Cell Cancer Tests
Table 8-11: Selected New Cancer Tests and Technologies
CHAPTER NINE: CANCER TESTS IN FLOW CYTOMETRY
Table 9-1: Selected flow cytometry innovations for cancer testing
CHAPTER TEN: CIRCULATING TUMOR CELLS IN CANCER DIAGNOSTICS
Table 10-1: Selected CTC Capture And Analysis Systems
CHAPTER ELEVEN: CANCER MOLECULAR ASSAYS
Table 11-1: Selected Commercial Molecular Cancer Tests
Table 11-2: Selected Molecular Instrumentation Innovations
Table 11-3: Selected RNA-Based Cancer Tests
Table 11-4: Selected Methylated DNA tests
CHAPTER TWELVE: PERSONALIZED CANCER TESTING ADVANCES IN PRECISION
Table 12-1: Most Common Cancer Drug/Gene Mutation Combinations
Table 12-2: Major Protein And Molecular Markers Used In Tissue Staining
Table 12-3: Selected Pharmacodiagnostic Histology Tests
Table 12-4: Selected Chemotherapy Resistance Tests




Read the full report:
The World Market for Cancer Diagnostics, 5th Edition: Precision and Personalized Testing Arrives

http://www.reportbuyer.com/pharma_healthcare/diagnostics/world_market_cancer_diagnostics_5th_edition_precision_personalized_testing_arrives.html

For more information:
Sarah Smith
Research Advisor at Reportbuyer.com
Email: query@reportbuyer.com
Tel: +44 208 816 85 48
Website: www.reportbuyer.com

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Source: PR Newswire



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