Disability and Poor Quality of Life Associated With Treatment Failure Gout Patients
New Study Published in the Journal of Rheumatology Examines Quality of Life and Disability in Treatment Failure Gout Patients
The study is the first to evaluate the quality of life in patients with treatment failure gout and appears in the May issue of the Journal of Rheumatology. TFG is defined as advanced gout in patients where conventional therapy is contraindicated or has been ineffective.
“Our study examined some of the most difficult to treat gout patients, many of whom regularly experience excruciating pain and struggle with co-morbid health disorders like metabolic and cardiovascular disease,” said
Treatment failure gout was shown to be associated with poor health-related quality of life and significant disability. Validated survey instruments for the assessment of patient-reported quality of life were used in this study which included Health Assessment Questionnaire-Disability Index and the SF-36. The TFG patients that were studied averaged 59 years in age. However, due to the poor quality of life associated with the disease, the reported results were more typical of Americans 74 years or older without TFG. Additionally, patient-reported perceptions of their gout-related pain and functioning were even more severe and more consistent than assessments of these same metrics reported by physicians.
About Savient Pharmaceuticals, Inc.
Savient Pharmaceuticals, Inc. is a specialty biopharmaceutical company focused on developing and marketing pharmaceutical products that target unmet medical needs in both niche and broader specialty markets. Savient’s product development candidate, KRYSTEXXA(TM) (pegloticase) for treatment failure gout, has reported positive Phase 1, 2 and 3 clinical data. Patient dosing in the Phase 3 clinical studies began in
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