Nutri-Med Logic Corp States Liver Health Improvement, in the Alcoholic Liver Disease, Has Less to Do With the Soy Protein, Rather is Due to the PPC Portion of the Soy.
Nutri-Med Logic Corp. states that nutritional benefits of soy, for the liver health improvement, in the cases of alcohol-induced accumulation of fat in the liver, arises from the Poly-enyl-phosphatidylcholine (PPC) portion of the soy and not the soy protein per se. PPC is a pure extract from soy and, for decades, has been recommended, at least in Europe, to improve liver and intestine health.
Miami, Florida (PRWEB) August 16, 2011
Nutri-Med Logic Corp: The recent study in the Journal of Nutritional Biochemistry (Aug. 1, 2011) attributes the reduction of the fat accumulation (liver health improvement) to the soy protein. As it relates to liver health, the nutritional benefits of soy is vested in its PPC portion and same has been well studied and documented, dating back to 1992 with Lipostabil (PPC). (1)
PPC (Poly-Enyl-Phosphatidylcholine) is the only component of soy that contains choline and, thus, is the most beneficial part of the soy for liver health.
PPC is also referred to as Essential Phospholipid “EPL” due to its high degree of Essential Polyunsaturated Fatty Acids.
Both choline part of the PPC and the PPC itself play important roles in healthy functioning of the Liver, specially when it come to alcohol.
Studies on the necessity of choline intake for those who drink alcohol dates back to 1954. (2)
Additionally Choline was declared an essential nutrient, meaning that the body does not make enough of this nutrient and thus it must be included in diet for the healthy functioning of the body.
PPC has an absorption rate of about 90% and by content contains 14.5% choline, making PPC, probably, the most effective and efficient source of choline.
PPC is suggested to provide nutritional (anti-oxidant) benefits for the gene Cytochrome P450 2E1 (CYP2E1), which is also called the oxidation gene. CYP2E1 is an important gene, necessary for elimination of foreign substances, such as alcohol. However, hyperactivity of this oxidative gene (CYP2E1) causes the transformation of stellate cells (cells that reserve vitamin A, mainly in liver and pancreas) to myofibroblasts. Over-expression (hyperactivity) of myofibroblasts would over-produce collagens, which could damage liver and pancreas. (3, 4)
PPC contains a component called di-lino-leoyl-phosphatidylcholine (DLPC), which abundant number of studies have pointed to its potential nutritional (anti-oxidant) benefits regarding Cytochrome P450 2E1 (CYP2E1). (5, 6, 7, 8, 9)
Studies have also suggested that a part of phosphatidylcholine (lyso-phosphatidylcholine) incorporates into the intestinal mucosa and could improve the healthy functioning of the mucous membranes of the intestinal tract. (10, 11)
It is important to note that PPC belongs to the Electrophilic Methyl Group, which gives it the ability to receive a hydrogen (H), mainly from the enzyme NADH, thus improving the redox (oxidation/reduction) homostasis. (12)
Excess NADH, amongst many other problems, creates a reductive stress, which is as damaging as oxidative stress.
A diet rich in PPC is very beneficial for liver health. However, nutrients cannot and should not be a substitute for medications. At the same time, it is not a secret that proper nutrients improve the overall health and thus confer valuable benefits.
It is also very important to note that these studies have not been evaluated by The FDA and, thus, one should not relate the cause of Alcoholic Liver Disease and/or accumulation of liver fat to the lack of PPC/Choline in diet; nor equate supplementation of PPC/Choline to prevention, treatment or cure.
Additionally, while there are no conclusive evidence that nutrient supplementation has beneficial effects on overall alcohol-mediated tissue damage but PPC has shown the most promising nutritional values for the liver health.
In conclusion, Nutri-Med Logic Corp. does not agree with the article in the Journal of Nutritional Biochemistry, which the soy benefits are vested in its protein, rather the benefits of the soy, as it relates to liver health, are due to its PPC portion.
Nutri-Med Logic Corp is a producer of dietary supplements that would be Essential in countering stress, inflammation, redox imbalance and hypomethylation “The Four Factors”; all of which affect the homeostasis of the body.
Nutri-Med Logic’s products are Formulated Based on Nutritional Logic, made from the highest quality raw materials that are manufactured in pharmaceutical facilities, encapsulated in pharmaceutical facilities and, also, packaged in pharmaceutical facilities.
1. Klin Med (Mosk). 1992 Jan;70(1):75-8.
2. Journal of experimental Medicine. December 1, 1954. Vol. 100 no. 6 615-627.
3. Journal of Biological Chemistry, Vol. 277, No. 12, Issue of March 22, pp. 9853″“9864, 2002.
4. Biochem and Biophys. Research Comm., Vol 300, Issue 1, 3 Jan. 2003, pp. 172-177.
5. Alcohol. 2004 Aug;34(1):9-19.
6. Drug Metab Rev. 2004 Oct;36(3-4):511-29.
7. Rocz Akad Med Bialymst. 2005;50:7-20.
8. J Hepatol. 2009 Jun;50(6):1236-46. Epub 2009 Apr 2.
9. Chin J Integr Med. 2010 Feb;16(1):23-7. Epub 2010 Feb 4.
10. Journal of Nutritional Biochemistry, Vol. 4, Issue 12, Dec. 1993,pp 690-694.
11. American Journal of Clinical Nutrition, 43: JANUARY 1986, pp 98-107.
12. British Journal of Nutrition. 2000. 85, 409-414.
For the original version on PRWeb visit: http://www.prweb.com/releases/prweb2011/8/prweb8722157.htm