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The Colorectal Drug Pipeline Update 2007 Lists All Drugs and Gives You a Progress Analysis on Each One

Posted on: Monday, 27 August 2007, 09:13 CDT

Research and Markets (http://www.researchandmarkets.com/reports/c66728) has announced the addition of "Colorectal Cancer Drug Pipeline Update 2007" to their offering.

Until a decade ago, 5FU/leucovorin formed the mainstay of colorectal cancer treatment but Camptosar and Eloxatin quickly established themselves as components of gold-standard therapy. The advent of Avastin and Erbitux heralded a new era in the disease management, and the emergence of other molecular targeted agents should further push survival to an unprecedented level in the coming years.

There are today more than 240 therapeutics targeting colorectal cancer, from early preclinical to marketed drugs. Colorectal Drug Pipeline Update lists all drugs and gives you a progress analysis on each one of them. Identified drugs are linked to 130 different targets. These targets are further categorized on the CD-ROM by 46 classifications of molecular function and their possible belonging to 19 different signaling pathways in the cell. Read more below on how the Colorectal Drug Pipeline Update is organized.

How May "Drug Pipeline Update" Be of Use?

Show investors/board/management that you are right on top of drug development progress in your therapeutic area.

Find competitors, collaborations partners, M&A candidates etc.

Jump start competitive drug intelligence operations

Excellent starting point for world wide benchmarking

Compare portfolio and therapy focus with your peers

Speed up pro-active in-/out licensing strategy work

Fast and easy way of tracking drugs using search engines; just one click and you may search the World Wide Web and PubMed for any drug.

Drug Pipeline Update is delivered to you as a CD-ROM application, which requires no installation on your computer. Please read more about application features and system requirements below.

Drug Pipeline Update at a Glance

Investigators: Includes more than 190 principal investigators plus their collaborators. There is direct access from inside the application to web pages of all principal investigators.

Note: You are able to sort and find drugs according to investigators and partners from drop-down menus in the application. You may also sort and find drugs according to country of investigator.

Drug name & Synonyms Lists commercial, generic and code names for drugs. In all more than 500 names

Developmental stage This Drug Pipeline Update contains more than 240 drugs in active development for the treatment of colorectal cancer:

> 16 marketed drugs

> 7 drugs in Phase III

> 85 drugs in Phase II

> 70 drugs in Phase I

> 60 drugs in Preclinical

Note: You are able to sort and find drugs according to developmental stage from drop-down menu in the application.

Indications Included colorectal drugs are in development for over 100 other indications

Note: You are able to sort and find drugs according to type of indication from drop-down menu in the application.

Targets Identified drugs are linked to 130 different targets, divided into 46 classifications of molecular function:

Carboxy-lyase activity

Catalytic activity

Cell adhesion molecule activity

Cofactor binding

Complement activity

Cysteine-type peptidase activity

Cytokine activity

DNA repair protein

DNA topoisomerase activity

DNA-directed DNA polymerase activity

DNA-methyltransferase activity

Extracellular matrix structural constituent

G-protein coupled receptor activity

Growth factor activity

Guanylate cyclase activity

Hormone activity

Hydrolase activity

Kinase activity

Ligand-dependent nuclear receptor activity

Ligase activity

Molecular function unknown

Motor activity

Oxidoreductase activity

Peptidase activity

Peroxidase activity

Phosphoric diester hydrolase activity

Protease inhibitor activity

Protein binding

Protein serine/threonine kinase activity

Protein threonine/tyrosine kinase activity

Protein tyrosine phosphatase activity

Protein-tyrosine kinase activity

Receptor activity

Receptor binding

Receptor signaling complex scaffold activity

Receptor signaling protein serine/threonine kinase activity

RNA-directed DNA polymerase activity

Serine-type peptidase activity

Structural constituent of cytoskeleton

Transcription factor activity

Transcription regulator activity

Transferase activity

Translation regulator activity

Transmembrane receptor activity

Transmembrane receptor protein tyrosine kinase activity

Unclassified

For more information visit http://www.researchandmarkets.com/reports/c66728

Source: Business Wire

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