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There Are Currently 165 Therapeutics Targeting Pancreatic Cancer, From Early Preclinical To Marketed Drugs

Posted on: Monday, 27 August 2007, 09:13 CDT

Research and Markets (http://www.researchandmarkets.com/reports/c66736) has announced the addition of "Pancreatic Cancer Drug Pipeline Update 2007" to their offering.

There are today more than 165 therapeutics targeting pancreatic cancer, from early preclinical to marketed drugs. Pancreatic Cancer Drug Pipeline Update lists all drugs and gives you a progress analysis on each one of them. Identified drugs are linked to 110 different targets. These targets are further categorized on the CD-ROM by 37 classifications of molecular function and their possible belonging to 19 different signaling pathways in the cell. Read more below on how the Pancreatic Cancer Drug Pipeline Update is organized.

How May Drug Pipeline Update Be of Use?

Show investors/board/management that you are right on top of drug development progress in your therapeutic area.

Find competitors, collaborations partners, M&A candidates etc.

Jump start competitive drug intelligence operations

Excellent starting point for world wide benchmarking

Compare portfolio and therapy focus with your peers

Speed up pro-active in-/out licensing strategy work

Fast and easy way of tracking drugs using search engines; just one click and you may search the World Wide Web and PubMed for any drug.

Drug Pipeline Update is delivered to you as a CD-ROM application, which requires no installation on your computer. Please read more about application features and system requirements below.

Drug Pipeline Update at a Glance

Investigators Includes more than 135 principal investigators plus their collaborators. There is direct access from inside the application to web pages of all principal investigators.

Note: You are able to sort and find drugs according to investigators and partners from drop-down menus in the application. You may also sort and find drugs according to country of investigator.

Drug name & Synonyms Lists commercial, generic and code names for drugs. In all more than 700 names

Developmental stage This Drug Pipeline Update contains more than 165 drugs in active development for the treatment of pancreatic cancer:

10 marketed drugs

15 drugs in Phase III

> 60 drugs in Phase II

> 45 drugs in Phase I

> 30 drugs in Preclinical

Note: You are able to sort and find drugs according to developmental stage from drop-down menu in the application.

Indications Included pancreatic cancer drugs are also in development for over 90 other indications.

Note: You are able to sort and find drugs according to type of indication from drop-down menu in the application.

Targets Identified drugs are linked to 110 different targets, divided into 37classifications of molecular function:

Carboxy-lyase activity

Catalytic activity

Cell adhesion molecule activity

Cysteine-type peptidase activity

Cytokine activity

DNA repair protein

DNA topoisomerase activity

DNA-directed DNA polymerase activity

Extracellular matrix structural constituent

G-protein coupled receptor activity

Growth factor activity

Hormone activity

Hydrolase activity

Kinase activity

Ligand-dependent nuclear receptor activity

Ligase activity

Lipase activity

Lipid phosphatase activity

Molecular function unknown

Oxidoreductase activity

Protein binding

Protein serine/threonine kinase activity

Protein threonine/tyrosine kinase activity

Protein-tyrosine kinase activity

Receptor activity

Receptor binding

Receptor signaling complex scaffold activity

RNA-directed DNA polymerase activity

Serine-type peptidase activity

Structural constituent of cytoskeleton

T cell receptor activity

Transcription factor activity

Transcription regulator activity

Translation regulator activity

Transmembrane receptor protein tyrosine kinase activity

Transporter activity

Unclassified

Identified targets are categorized into 18 different primary and alternate localizations:

Centrosome

Clathrin-coated vesicle

Cytoplasm

Cytoskeleton

Cytosol

Endoplasmic reticulum

Endosome

Extracellular

Golgi apparatus

Integral to membrane

Lysosome

Mitochondrial membrane

Mitochondrion

Nucleolus

Nucleus

Plasma membrane

Secreted

Secretory granule

Note: You are able to sort and find drugs according to target name, molecular function of target, and target localization from drop-down menus in the application.

For more information visit http://www.researchandmarkets.com/reports/c66736

Source: Business Wire

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