Blood Transfusion Increases Coronary Syndrome Death Rate
Posted on: Friday, 3 December 2004, 03:00 CST
A weekly round-up of the latest research and scientific reports from the nursing and medical journals
Blood transfusion in people with acute coronary syndromes is associated with higher mortality, researchers from the United States have found.
The researchers analysed the findings of three major studies involving 24, 112 people admitted to hospital with acute coronary syndromes. They were divided into two groups: those who received blood during admission (n=2,401) and those who did not. The main outcome measure was 30-day mortality.
Patients who underwent transfusion were older and had more co- morbid disease and also had a significantly higher unadjusted 30- day mortality (8 versus 3.08 per cent), myocardial infarction (MI) (25.16 versus 8.16 per cent) and death/MI (29.24 versus 10.02 per cent) compared with those who did not have transfusions. After adjustment, blood transfusion was associated with an increased hazard ratio for 30-day mortality (hazard ratio 3.94) and 30-day death/myocardial infarction (hazard ratio 2.92).
Rao S et al (2004) Relationship between blood transfusion and clinical outcomes in patients with acute coronary syndromes. Journal of the American Medical Association. 292, 13, 1555-1562.
Copyright RCN Publishing Company Ltd. Nov 17-Nov 23, 2004
Source: Nursing Standard
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