2009 Study Linking Mouse Virus To Chronic Fatigue Could Be False
September 23, 2011

2009 Study Linking Mouse Virus To Chronic Fatigue Could Be False


Scientists who linked a mouse virus to chronic fatigue syndrome may have had some false information during their original 2009 study.

New research published by Science on Thursday cast doubt on 2009 study published in the same journal that linked chronic fatigue syndrome with the XMRV virus.

The initial 2009 results claimed that XMRV was found in the blood of two-thirds of patients with chronic fatigue syndrome.

However, Science ran two reports refuting the 2009 study in May 2011, along with an "editorial expression of concern".

The editorial said the validity of the original chronic fatigue study by research teams "is now in question."

One of the studies by the National Cancer Institute suggested the finding was due to contaminated lab samples. 

Dr. Robert Silverman and Jaydip Das Gupta of the Cleveland Clinic, who were co-authors on the original 2009 paper in Science, double-checked their experiments and found some of the samples from chronic fatigue patients were contaminated with a laboratory form of XMRV genetic material.

The researchers have since retracted tables and figures from the study.

The study authors still believe other data in the paper support their original conclusions, but Science reported that it still stands by its "editorial expression of concern" it had written in May.


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