September 27, 2011
Rhode Island Hospital Finds Lack Of Testing For Legionella
Current recommendations for testing missed 41 percent of cases
A new study from Rhode Island Hospital shows that guidelines concerning testing patients for possible community-acquired pneumonia due to Legionella may underestimate the number of cases being seen by clinicians. The study found that if testing was only done in patients felt to be at increased risk of Legionnaires' disease based on such guidelines, more than 40 percent of Legionella cases could be missed based on this single-center study. The researchers suggest more widespread testing for Legionella in patients admitted to hospitals with pneumonia. The study is published in BMC Infectious Diseases and is now available online in advance of print.
Leonard Mermel, DO, medical director of the epidemiology and infection control department at Rhode Island Hospital, is the senior author of this retrospective study that identified nearly 4,000 patients with a primary or secondary diagnosis of pneumonia in an 18-month period. Of those patients, 35 percent had a Legionella urine antigen testing or had a Legionella culture performed. In addition, 44 percent of patients who had a bronchoscopy had a specimen sent for Legionella culture and/or had Legionella urine antigen testing. Of the patients with pneumonia due to Legionella, only 22 percent met the IDSA/ATC criteria recommending Legionella testing.
Mermel says, "This single-center study suggests that current recommendations for Legionella testing will result in missed cases. More widespread testing will identify additional cases allowing focused antimicrobial therapy and will alert public health officials of such Legionella cases".
Co-author Brian Hollenbeck, M.D., adds, "Legionella is a severe cause of community- and hospital-acquired pneumonias. We hope that this study will raise awareness of the need for more comprehensive Legionella testing in patients who are hospitalized with pneumonia."
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