October 31, 2011
Drug Fails To Benefit Patients With Kidney Disease
(Ivanhoe Newswire) — A drug meant to be beneficial, is suddenly found not so useful. According to a study, the drug sulodexide that was hoped to be a promising new drug to protect the kidneys has failed to benefit diabetes patients with kidney disease.
The drug sulodexide is actually a naturally occurring compound had has been used for more than 20 years to treat various heart conditions. Previous research indicates that sulodexide reduces excretion of protein in the urine, which is a hallmark of kidney disease.
"In view of the negative results of Sun-MICRO trial and the data analysis from this study, it is tempting to conclude that sulodexide has no therapeutic benefit in type 2 diabetic nephropathy," the authors wrote.
Kidney disease due to diabetes is the most common cause of kidney failure in developed countries. The number of patients with type 2 diabetes is expected to double and reach 366 million individuals worldwide by 2030.
SOURCE: Journal of the American Society Nephrology