December 21, 2011
New Evidence That Bacteria In Large Intestine Have A Role In Obesity
Bacteria living in people's large intestine may slow down the activity of the "good" kind of fat tissue, a special fat that quickly burns calories and may help prevent obesity, scientists are reporting in a new study. The discovery, published in ACS' Journal of Proteome Research, could shed light on ways to prevent obesity and promote weight loss, including possible microbial and pharmaceutical approaches, the authors said.
Sandrine P. Claus, Jeremy K. Nicholson and colleagues explain that trillions of bacteria live in the large intestine of healthy people, where they help digest food and make certain vitamins. In recent years, however, scientists have realized that these bacteria do more – they interact with the rest of the body in ways that affect the use of energy and its storage as fat and finely tune the immune system. Claus and Nicholson decided to see how intestinal bacteria might affect the activity of brown fat. The "good" fat that burns calories quickly before they can be stored as fat, brown fat exists in small deposits in the neck area and elsewhere – not like "white fat" in flab around the waist and buttocks. No one had checked to see if those bacteria could have an effect on brown fat, the researchers noted.
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