February 1, 2012
Rate Of Follow-Up Surgeries After Partial Mastectomy Varies Greatly
Findings could affect both cancer recurrence and overall survival rates
A new study reveals substantial differences — by both surgeon and institution — in the rates of follow-up surgeries for women who underwent a partial mastectomy for treatment of breast cancer.
Those differences, which cannot be explained by a patient´s medical or treatment history, could affect both cancer recurrence and overall survival rates, according to the study led by Laurence McCahill, M.D. of Van Andel Research Institute, Michigan State University´s College of Human Medicine, and the Richard J. Lacks Cancer Center.
The research appears in the Feb. 1 edition of the Journal of the American Medical Association.
“A partial mastectomy is one of the most commonly performed cancer operations in the United States,” said McCahill. “Currently, there are no readily identifiable quality measures that allow for meaningful comparisons of breast cancer surgical outcomes among surgeons and hospitals.
“But the current U.S. health care environment calls for increasing accountability for physicians and hospitals as well as transparency of treatment results.”
About three-fourths of women battling breast cancer have a partial mastectomy, and nearly one in four of them at some point have another surgery (re-excision) to remove additional tissue. A partial mastectomy intends to remove cancerous cells while maintaining maximum cosmetic appearance of the breast, but failure to remove all the cells at the initial operation requires additional surgery.
The additional operations can produce considerable psychological, physical and economic stress for patients and delay use of recommended supplemental therapies, according to the study, which measured variation in re-excision rates across hospitals and surgeons from 2003 to 2008. The study included more than 2,200 women with invasive breast cancer from four sites across the country.
The results show rates of re-excision varied widely and were not tied to any discernible characteristics for the patient. The study highlights the value of multicenter observational studies to pinpoint the variability in health care across different regions and health systems, McCahill said.
“While the long-term effect of this variability is beyond the scope of our study, it is feasible that cancer recurrence and overall survival could be affected by differences in initial surgical care,” he said. “The wide level of unexplained clinical variation itself represents a potential barrier to high-quality and cost-effective care of patients with breast cancer.”
The study was funded by a $1.1 million National Institutes of Health grant to Van Andel Research Institute via the American Recovery and Reinvestment Act of 2009. The two-year project led by Dr. McCahill was entitled "Improving Breast Cancer Surgery Quality through a Collaborative Surgery Database."
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