April 27, 2012
Vitamin D, A Double Edged Sword for Osteoporosis
(Ivanhoe Newswire) -- Vitamin D is known for helping create strong bones and is a key regulator of serum calcium levels. Recent studies, however, have not offered much proof that Vitamin D supplements prevents bone fractures.
Calcium is obtained through diet and absorbed through the intestine and into the blood stream. Calcium is responsible for a variety of physiological processes, not just building bone. Vitamin D is detected by bone and intestinal cell receptors and it regulates the level of calcium in the blood stream while determining how much should be stored in the skeleton.A recent study used mice to investigate how vitamin D affects the skeleton when serum calcium levels are down. Researchers recorded that the mice had normal serum calcium levels even when given a low-calcium diet. Also, the study showed that vitamin D stimulated bone cells to produce factors that removed calcium from the bone in order to maintain normal serum calcium levels. Therefore, vitamin D can maintain serum calcium levels, but it can also help promote bone density loss!
SOURCE: Journal of Clinical Investigation, April 2012