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Last updated on April 20, 2014 at 14:04 EDT

Second Quarter 2012 Results Date Notification – August 1, 2012

July 19, 2012

DUBLIN, July 19, 2012 /PRNewswire/ –

Shire plc (LSE: SHP, NASDAQ: SHPG), the global specialty biopharmaceutical company,
will announce second quarter 2012 earnings on Wednesday August 1, 2012.

           Results press release will be issued at:               12:00 BST / 07:00 EDT
           Investor conference call time:                         14:00 BST / 09:00 EDT

Live conference call for investors:

Angus Russell, Chief Executive Officer and Graham Hetherington, Chief Financial
Officer will host the investor and analyst conference call at 14:00 BST/9:00 EDT.

The details of the conference call are as follows:

           UK dial in:               08082370030
           US dial in:               1866-928-7517 or 1-718-873-9077
           International dial in:    +44(0)2031394830
           Password/Conf ID:         16001010#
           Live Webcast:             http://www.shire.com/shireplc/en/investors

Replay:

A replay of the presentation will be available for two weeks by phone and by webcast
for three months. Details can be found on our Investor Relations website

http://www.shire.com/shireplc/en/investors.

For further information please contact:

Notes to editors

SHIRE PLC

Shire’s strategic goal is to become the leading specialty biopharmaceutical company
that focuses on meeting the needs of the specialist physician. Shire focuses its business
on attention deficit hyperactivity disorder, human genetic therapies, gastrointestinal
diseases and regenerative medicine as well as opportunities in other therapeutic areas to
the extent they arise through acquisitions. Shire’s in-licensing, merger and acquisition
efforts are focused on products in specialist markets with strong intellectual property
protection and global rights. Shire believes that a carefully selected and balanced
portfolio of products with strategically aligned and relatively small-scale sales forces
will deliver strong results.

For further information on Shire, please visit the Company’s website:

http://www.shire.com.

        Investor Relations

        Souheil Salah (ssalah@shire.com), +44(0)1256-894-160
        Erin K. Kelly (erikelly@shire.com), +1-781-482-9541

SOURCE Shire plc


Source: PR Newswire