July 27, 2012

N-3 Fatty Acids and Cardiovascular Disease

(Ivanhoe newswire) - Cardiovascular disease is the leading cause of death worldwide. While research has shown that increasing the amount of n-3 fatty acids within your diet could help lower the risk of cardiovascular disease, a new research shows that might not be all true.

The new blind, randomized, placebo study looked at 12,536 patients of at least 50 years of age with a high risk for cardiovascular events that has impaired fasting glucose, impaired glucose tolerance, or diabetes. Patients were randomly assigned a 1-g capsule containing at least 900 mg of ethyl esters of n—3 fatty acids or placebo daily. They also received either insulin glargine or standard care.

During a median follow up of 6.2 years, the incidence of the primary outcome was not significantly decreased among patients receiving n—3 fatty acids, as compared with those receiving placebo. The use of n—3 fatty acids also had no significant effect on the rates of major vascular events.

Researchers concluded daily supplementation with 1 g of n—3 fatty acids did not reduce the rate of cardiovascular events in patients at high risk for cardiovascular events.

SOURCE: The New England Journal of Medicine, July 2012