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3 out of 4 Britons Value Mental Wellness Over Weight and Sexual Drive, but Only 40% Would Seek Help From Their Doctor

April 17, 2013

LONDON, April 18, 2013 /PRNewswire/ –

60% unaware of alternative depression treatments, other than taking pills

Leading London Centre [http://www.psychiatrycentre.co.uk ] is the first and

only to launch drug-free treatment for depression in UK

Research launched today found that Britons value their mental wellness over their
weight, sexual drive, fitness and gut health. According to results from a survey of 1,000
people in the UK, 77% of Britons value or highly value their mental health, yet only 40%
would consult their doctor if their condition started to impact their everyday life.[1] Of
those surveyed, nearly three out of four either suffered from depression or know someone
who has, but less than half (40%) were aware of alternative treatments for the condition
which don’t involve taking pills.

Today, to coincide with National Depression Awareness Week, The London Psychiatry
Centre [http://www.psychiatrycentre.co.uk ] is launching a drug-free and effective
treatment for depression. Repetitive Transcranial Magnetic Stimulation
[http://www.psychiatrycentre.co.uk/our-services/repetitive-transcranial-magnetic-stimulation-rtms ]
(rTMS) is changing the way depression is managed. Offered widely at high profile
hospitals and centres in the US, including Johns Hopkins and Harvard’s McLean Hospital,
The London Psychiatry Centre
[http://www.psychiatrycentre.co.uk/our-services/repetitive-transcranial-magnetic-stimulation-rtms ]
is the first and only clinic to offer rTMS treatment in the UK. Dr Rafael Euba,
Consultant Psychiatrist at the Centre said, “Through medical research we are continuously
finding better, more effective ways of treating the condition. It’s important that
patients with depression in the UK are able to benefit from these innovative options.”

Around one in ten people in the UK suffer from depression at some point in their
lifetime, which is over six million people, a number equivalent to the entire population
of Rio de Janeiro. More frequently prescribed treatments don’t always work or are not
suitable, plus their side-effects can cause weight gain, low sex drive and even heart
problems. Dr Euba noted, “It’s important to highlight that up to 70% of people with
depression will continue to experience symptoms despite taking medication and/or receiving
psychotherapy. This is known as treatment-resistant depression, which is very common.”

rTMS is a non-invasive and painless method of brain stimulation that relies on
electromagnetic induction using an insulated coil placed over the scalp, focused on an
area of the brain thought to play a role in mood regulation.[2] The treatment is licenced
in the UK for people with depression who have not seen a satisfactory response to two
antidepressants, giving them the opportunity to experience relief without the side-effects
that may be associated with more extreme or chemical alternatives.[3],[4],[5],[6],[7
]According to clinical research, 1 in 2 patients who were unresponsive to antidepressant
medication experience a significant improvement in their depressive symptoms when treated
with rTMS, while 1 in 3 experiences recovery.[6] Patients with resistant depression
treated with rTMS also benefited from a shorter recovery time of around 4 weeks. This
compares to those trying alternative medications who would typically experience
improvements in around 6-9 months, if recognised treatment protocols are followed.

One of the patients who recently completed the four week treatment said, “I feel like
the person I used to be 30 years ago! I’ve got my brain back. The treatment shifted the
way I approach problems and feels like it almost blocks my negative way of thinking.”
After two weeks of treatment, not only had the patient stopped taking her medication
completely, she no longer felt the dread she woke up with every day and decided to start
doing new things, feeling optimistic about her future.

Since launching rTMS at The London Psychiatry Centre
[http://www.psychiatrycentre.co.uk/our-services/repetitive-transcranial-magnetic-stimulation-rtms ]
, all patients completing treatment have had an improvement in their condition.[8]
If you or a person you know would like to find out more information about treatment with
rTMS visit The London Psychiatry website at http://www.psychiatrycentre.co.uk.

Notes to Editors

About depression

Around one in ten people in the UK suffer needlessly from depression at some point in
their lifetime and it is thought that a large number of people are still undiagnosed. The
condition can impact every aspect of a person’s life including their ability to work,
establish and maintain relationships and their overall quality of life. Depression has
also been associated with an increased risk of cardiovascular disease, such as heart
attack and stroke.[9],[10],[11],[12]

About rTMS

rTMS is a non-invasive method of brain stimulation that relies on electromagnetic
induction using an insulated coil placed over the scalp, focused on an area of the brain
thought to play a role in mood regulation.[13] The coil generates brief magnetic pulses,
which pass easily and painlessly through the skull and into the brain. The pulses
generated are comparable to those generated by magnetic resonance imaging (MRI) machines.
When these pulses are administered in rapid succession, it is referred to as “repetitive
TMS ” or “rTMS”, which can produce longer lasting changes in brain activity.[4] Clinical
studies have consistently shown that rTMS is effective in treatment-resistant
depression,[6],[14],[15],[16],[17],[18],[19],[20]rTMS has been licensed in the UK, to
treat patients with depression who have not seen a satisfactory response to 2
antidepressants.

In comparison to more extreme alternatives such as electroconvulsive therapy (ECT),
rTMS is considerably less invasive, has minimal side effects,[21] and has proven to offer
equivalent health benefits.[22] rTMS is therefore seen as a safe middle step in people who
do not respond to antidepressants, before considering ECT. In the US, rTMS is offered as a
standard therapy in a number of high profile health clinics including John Hopkins and the
Mayo Clinic.

rTMS treatment is well tolerated and non-invasive, requiring only five sessions per
week for between two to six weeks, sometimes followed by maintenance or top-up treatment 6
- 12 months later.[19],[20] Patients also recover faster in around 4 weeks, compared to
those who tried different forms of medication, who took between 6-9 months to see
significant improvements. Patients don’t need to go to hospital to receive treatment with
rTMS; the simple procedure is performed in an outpatient clinic.

About The London Psychiatry Centre [http://www.psychiatrycentre.co.uk. ]

The London Psychiatry Centre offers an integrated and complete service addressing
every need associated with mental health. This includes psychiatric, psychological,
therapeutic and social aspects of a patient. Consultant Psychiatrists, Psychologists and
Psychotherapists along with nutritionists, coaches, personal trainers and therapists are
on site to help.

To find out more information about The London Psychiatry, visit the website -

http://www.psychiatrycentre.co.uk.

References

1. Results of a survey of 1,000 people in the UK, conducted in March 2013 by OnePoll

2. George M, Taylor J, Baron Short E, The expanding evidence base for rTMS treatment
of depression, Current Opinion Psychiatry, 2013,26:13-18

3. O’Reardon JP, Solvason HB, Janicak PG, et al.Efficacy and safety of transcranial
magnetic stimulation in the acute treatment of major depression: a multisite randomized
controlled trial. Biol Psychiatry 2007; 62:1208-1216.

4. Demitrack MA, Thase ME. Clinical significance of transcranial magnetic stimulation
(TMS) in the treatment of pharmacoresistant depression: synthesis of recent data.
Psychopharmacol Bull 2009; 42:5-38.

5. George MS, Lisanby SH, Avery D, et al. Daily left prefrontal transcranial magnetic
stimulation therapy for major depressive disorder: a sham-controlled randomized trial.
Arch Gen Psychiatry 2010; 67:507-516.

6. McDonald WM, Durkalski V, Ball ER, et al.Improving the antidepressant efficacy of
transcranial magnetic stimulation: maximizing the number of stimulations and treatment
location in treatment-resistant depression. Depress Anxiety 2011; 28:973-980

7. Mantovani A, Pavlicova M, Avery D, et al.Long-term efficacy of repeated daily
prefrontal transcranial magnetic stimulation (TMS) in treatment-resistant depression.
Depress Anxiety 2012; 29:883-890

8. Data on file

9. Ludescher B, Machann J, Eschweiler GW, Thamer C, Maenz C, Hipp A, Claussen CD, &
Schick F (2011). Active depression is associated with regional adiposity in the upper
abdomen and the neck. International journal of psychiatry in medicine, 41 (3), 271-80
PMID: 22073766 [http://www.ncbi.nlm.nih.gov/pubmed/22073766 ]

10. Rubin RR, Gaussoin SA, Peyrot M, DiLillo V, Miller K, Wadden TA, West DS, Wing RR,
Knowler WC, & Look AHEAD Research Group (2010). Cardiovascular disease risk factors,
depression symptoms and antidepressant medicine use in the Look AHEAD (Action for Health
in Diabetes) clinical trial of weight loss in diabetes. Diabetologia, 53 (8), 1581-9 PMID:
20422396 [http://www.ncbi.nlm.nih.gov/pubmed/20422396 ]

11. Rutledge T, Linke SE, Krantz DS, Johnson BD, Bittner V, Eastwood JA, Eteiba W,
Pepine CJ, Vaccarino V, Francis J, Vido DA, & Merz CN (2009). Comorbid depression and
anxiety symptoms as predictors of cardiovascular events: results from the NHLBI-sponsored
Women’s Ischemia Syndrome Evaluation (WISE) study. Psychosomatic medicine, 71 (9), 958-64
PMID: 19834049 [http://www.ncbi.nlm.nih.gov/pubmed/19834049 ]

12. Shah AJ, Veledar E, Hong Y, Bremner JD, & Vaccarino V (2011). Depression and
history of attempted suicide as risk factors for heart disease mortality in young
individuals. Archives of general psychiatry, 68 (11), 1135-42 PMID: 22065529
[http://www.ncbi.nlm.nih.gov/pubmed/22065529 ]

13. George M, Taylor J, Baron Short E, The expanding evidence base for rTMS treatment
of depression, Current Opinion Psychiatry, 2013,26:13-18

14. Li CT, Wang SJ, Hirvonen J, et al. Antidepressant mechanism of add-on repetitive
transcranial magnetic stimulation in medication-resistant depression using cerebral
glucose metabolism. J Affect Disord. 2010, 127(1-3):219-29

15. Blumberger DM, Mulsant BH, Fitzgerald PB, et al. A randomized double-blind
sham-controlled comparison of unilateral and bilateral repetitive transcranial magnetic
stimulation for treatment-resistant major depression. World J Biol Psychiatry.
2012;13(6):423-35

16. Fitzgerald PB, Hoy K, Gunewardene R, et al. A randomized trial of unilateral and
bilateral prefrontal cortex transcranial magnetic stimulation in treatment-resistant major
depression. Psychol Med. 2010;41:1187-1196

17. Galletly C, Gill S, Clarke P, Burton C, Fitzgerald PB. A randomized trial
comparing repetitive transcranial magnetic stimulation given 3 days/week and 5 days/week
for the treatment of major depression: is efficacy related to the duration of treatment or
the number of treatments? Psychol Med. Sep 13 2011:1-8.

18. Holtzheimer PE, 3rd, McDonald WM, Mufti M, et al. Accelerated repetitive
transcranial magnetic stimulation for treatment-resistant depression. Depress Anxiety. Oct
2010;27(10):960-963.

19. Carpenter LL, Janicak PG, Aaronson ST, Boyadjis T, Brock DG, Cook IA, Dunner DL,
Lanocha K, Solvason HB, Demitrack MA. Transcranial magnetic stimulation (TMS) for major
depression: a multisite, naturalistic, observational study of acute treatment outcomes in
clinical practice. Depress Anxiety. 2012;29(7):587-96.

20. Connolly KR, Helmer A, Cristancho MA, Cristancho P, O’Reardon JP. Effectiveness of
transcranial magnetic stimulation in clinical practice post-FDA approval in the United
States: results observed with the first 100 consecutive cases of depression at an academic
medical center. J Clin Psychiatry. 2012;73(4):e567-73.

21. Eranti S, Mogg, et al. [http://www.ncbi.nlm.nih.gov/pubmed/17202547 ] A
Randomized, Controlled Trial with 6-Month Follow-Up of Repetitive Transcranial Magnetic
Stimulation and Electroconvulsive Therapy for Severe Depression”. American Journal of
Psychiatry, 2007164 (1): 73-8122. Coverage Policy Analysis: Repetitive Transcranial
Magnetic Stimulation (rTMS), The New England Comparative Effectiveness Public Advisory
Council, completed by: The Institute for Clinical and Economic Review. June 2012

SOURCE The London Psychiatry Centre


Source: PR Newswire