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Last updated on April 18, 2014 at 14:58 EDT

Molecular Cytogenetics Market is Expected to Reach USD 1.97 Billion Globally in 2019: Transparency Market Research

August 21, 2013

ALBANY, New York, August 21, 2013 /PRNewswire/ –

According to a new market report published by Transparency Market Research
(http://www.transparencymarketresearch.com) “Molecular Cytogenetics Market
(Technologies: FISH and aCGH; Applications: Genetic Disorders, Cancer and Personalized
Medicine) – Global Industry Analysis, Size, Share, Growth, Trends and Forecast, 2013 -
2019,” the global molecular cytogenetics market was valued at USD 469.2 million in 2012
and is estimated to reach a market worth USD 1.97 billion in 2019 at a CAGR of 23.4% from
2013 to 2019.

Browse the full report at

http://www.transparencymarketresearch.com/molecular-diagnostics-market.html

Molecular cytogenetics is emerging as an indispensable tool in the field of research
and diagnosis. Until the advent of molecular cytogenetics techniques in 1980s, chromosomal
analysis was mainly based on banding patterns. Although, the traditional banding
techniques encountered problems such as low resolution and poor quality analysis. However,
breakthrough in fluorescence in situ hybridization (FISH) and array-comparative genomic
hybridization (aCGH) techniques has enhanced the diagnosis of chromosomal anomalies
particularly in tumor and hematological malignancies. Nowadays, cytogenetics techniques
are being considered mandatory in diagnosis and prognosis of leukemia. The techniques are
considered as a standard laboratory test since they provide global screening of
abnormalities. The scope of molecular cytogenetics is increasing with the rising cancer
incidences worldwide and growing popularity of personalized medicines.

The ability of FISH technique to study cells at an interphase stage of the cell cycle
has made the technique a breakthrough in molecular cytogenetics field. FISH technique is
used in the research of diverse applications such as cancer, cardiovascular and genetic
disorder. The impetus of FISH technique is a direct result of improved understanding of
sequence, structure and function of human genome. Similarly, supported by technological
advancements in fluorescent microscopes and digital imaging, FISH technique has emerged as
a preferred tool in molecular cytogenetics. The technique facilitates the analysis of
sub-chromosomal regions and the identifications of small translocations thereby, routinely
used in clinical applications. Owing to the techniques’ sensitivity and specificity, FISH
is significantly used in number of cytogenetic and pathological laboratories.

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The advent of aCGH is ushering new standards for the analysis of genome. The
technology has turned out to be a greatest driver for the molecular cytogenetics market as
it is overcoming the resolution problems associated with traditional banding techniques.
aCGH is poised to witness a significant growth in the market and is likely to emerge as
the fastest growing technology segment. aCGH has propelled the cytogenetics market from
the microscopes to computers and thus, facilitated simultaneous analysis of thousands of
discrete regions of the genome. Similarly, the technique is gaining popularity as one
assay performed on this technique is comparable to thousands of FISH experiments and
hence, saves time and cost. Moreover, the technique is expected to rapidly supplant FISH
technique owing to further technological advancements in the technique. Likewise,
increasing sensitivity of the aCGH technique is preferred as a primary diagnosis tool
followed by validation with FISH. The technique is emerging as a powerful tool for high
resolution analysis of sub-microscopic chromosomal abnormalities. aCGH is also evolving as
a method of choice for molecular cytogenetics by the researchers owing to its work flow
advantages and cost effectiveness.

North America accounts for the largest share of the molecular cytogenetics market
followed by the European region. The markets for these regions are driven by factors such
as increased level of public awareness, rising cancer incidences and large number of
research institutes engaged in cytogenetics field. However, Asia-Pacific region is likely
to emerge as the fastest growing region over the analysis period. Cancer diagnosis is
likely to witness a significant growth and emerge as the fastest growing segment during
analysis period with a CAGR of more than 20%.

The growing demand for molecular cytogenetics techniques in research and data
interpretation has resulted in quick expansion of manufacturers’ product portfolio. The
manufacturers are focused on building aggressive strategies for the development of
innovative products that would cater research and diagnostic sectors. The vendors are
eager to tap the emerging regions and end-users of this market. Major players engaged in
development of innovative molecular cytogenetics techniques are Abbott laboratories,
Affymetrix, Inc., Applies Spectral Imaging, BI Biological Industries, Life Technologies
Corporation, Roche Diagnostics, Oxford Gene Technology, Illumina, Inc., among others.

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The molecular cytogenetics market is segmented as follows:

        - Molecular Cytogenetics Market, by Technology

FISH

aCGH

        - Molecular Cytogenetics Market, by Application

Genetic Disorders

Cancer

Personalized Medicine

Others

        - Molecular Cytogenetics Market, by Geography

North America

Europe

Asia-Pacific

RoW

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Transparency Market Research [http://www.transparencymarketresearch.com ] is a global
market intelligence company, providing global business information reports and services.
Our exclusive blend of quantitative forecasting and trends analysis provides
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experienced team of Analysts, Researchers, and Consultants, who use proprietary data
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Our data repository is continuously updated and revised by a team of research experts,
so that it always reflects the latest trends and information. With a broad research and
analysis capability, Transparency Market Research employs rigorous primary and secondary
research techniques in developing distinctive data sets and research material for business
reports.

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