Last updated on April 21, 2014 at 5:21 EDT

Washington University Hospital enrolls first patient in iMRI database expansion

September 24, 2013

Multiple neurosurgical centers to evaluate long-term effectiveness,
efficacy, and value of intraoperative MRI for brain tumor surgery

MINNEAPOLIS, Sept. 24, 2013 /PRNewswire/ – IMRIS Inc. (NASDAQ: IMRS; TSX: IM)
(“IMRIS” or the “Company”) today announced that the first brain tumor
patient was enrolled by the Washington University School of Medicine,
St. Louis, MO, for an expanding clinical neurosurgical database
designed to study the use and benefits of ceiling-mounted high-field
intraoperative MRI. A collaboration with Washington University, the
IMRIS Multicenter iMRI Neurosurgery Database (I-MiND) will focus on the
value of advancing the science, outcomes, indications and economics for
iMRI through patient data and comparative data from partnering centers.

“There is nothing else out there of this scale utilizing multiple
centers for evaluating intraoperative MRI,” said Dr. Michael Chicoine,
I-MiND Principal Investigator and Associate Professor of Neurological
Surgery at Washington University School of Medicine. “This will be
critical in determining the long-term value and patient outcomes for
iMRI in neurosurgery. Data from multiple sites will greatly reduce the
time of collection, and therefore give us a lot of useful clinical
information quickly, including new applications of the technology and
emerging techniques in neurosurgery.”

Chicoine said the research objectives include examining long-term
effectiveness of using iMRI on extent of resection, need for additional
surgery, survival and other outcome measures; improving delivery and
efficiency of procedures in the OR suite; and enhancing understanding
of the variability, progression and natural history of different
pathologies treated while guided by iMRI.

Washington University will serve as the coordinating center and invite
other hospitals that use iMRI to participate. The university has been a
leader in advancing the use of iMRI in neurosurgery with the IMRIS
VISIUS(®) Surgical Theatre which allows imaging of the patient in the middle of
the surgery without moving them from the OR table. The ceiling-rail
mounted iMRI moves to the patient while the procedure is still being

“Numerous studies of various iMRI devices have shown improvement in
extent of resection in surgeries for various types of brain surgeries
which lead to improved patient outcomes,” Chicoine said. “However, this
data has come mostly from retrospective data collection rather than
prospective collection which would be more accurate in assessing the
advantages or disadvantages of iMRI.”

I-MiND is an expansion of a three-year educational grant IMRIS made to
collect information on more than 700 cases from 2008-2011 at Washington
University. This led to the first published papers on use of the IMRIS
iMRI for awake craniotomies in 2011. Key excerpts from this study show
the VISIUS iMRI improves tumor resection and enhances safety in terms
of airway control, monitoring and head fixation with the intent of
improving precision, efficacy and safety of the neurosurgical

Inside a VISIUS Surgical Theatre, neurosurgeons have on-demand access to
real-time and diagnostic quality MR imaging and data at any or multiple
points during the procedure. The surgeon can visualize, evaluate and
confirm results while modifying treatment without case interruption.

“IMRIS is committed to investing in the future of neurosurgery,” said
IMRIS CEO Jay D. Miller. “This database will continue to affirm the
value of intraoperative MRI in a wide array of neurosurgical cases and
provide information to help guide emerging surgical techniques. We are
proud to have the VISIUS Surgical Theatre as the technology platform
upon which such important scientific evidence will be built.”

About Washington University School of Medicine

Washington University School of Medicine’s 2,100 employed and volunteer
faculty physicians also are the medical staff of Barnes-Jewish and St.
Louis Children’s hospitals. The School of Medicine is one of the
leading medical research, teaching and patient care institutions in the
nation, currently ranked sixth in the nation by
U.S. News & World Report. Through its affiliations with Barnes-Jewish and St. Louis Children’s
hospitals, the School of Medicine is linked to BJC HealthCare.


IMRIS (NASDAQ: IMRS; TSX: IM) is a global leader in providing image
guided therapy solutions through its VISIUS Surgical Theatre – a
revolutionary, multifunctional surgical environment that provides
unmatched intraoperative vision to clinicians to assist in decision
making and enhance precision in treatment. The multi-room suites
incorporate diagnostic quality high-field MR, CT and angio modalities
accessed effortlessly in the operating room setting. VISIUS Surgical
Theatres serve the neurosurgical, spinal, cardiovascular and
cerebrovascular markets and have been selected by 54 leading medical
institutions around the world.


Source: PR Newswire