Last updated on April 18, 2014 at 6:54 EDT

Indivumed Sells Inostics, the plasma-DNA Company, to Sysmex and Expands its Clinical Research Service and Patient Diagnostics Business

September 25, 2013

HAMBURG, Germany, September 25, 2013 /PRNewswire/ –

Indivumed GmbH (“Indivumed”), based in Hamburg, Germany, announces that 100% of all
shares of Inostics GmbH and its Baltimore, US-based subsidiary Inostics Inc. (“Inostics”),
have been sold to Sysmex Corporation (Headquarter in Kobe, Japan).

Inostics possesses advanced genetic testing technologies, such as ultra-sensitive
digital PCR technology for detecting cancer cell DNA directly from blood – a “liquid
biopsy” process as opposed to tissue testing. By acquiring this technology, Sysmex plans
to develop on a global basis assay services that Inostics already provides. Sysmex’s
companion diagnostics activities in collaboration with pharmaceutical companies will be
enhanced as well.

In 2008, following a five year collaboration with Dr. Bert Vogelstein and his team at
Johns Hopkins University in Baltimore, MD, Indivumed and the scientists at Johns Hopkins
University together founded Inostics GmbH in Hamburg, Germany, to commercialize the
“BEAMing-Technology”. “Having established a solid foundation to enable the rapid growth of
Inostics, the overwhelming acceptance of this groundbreaking technology by pharmaceutical
companies and the medical community demanded a global growth strategy and search for a
strategic partner. We are delighted to have found with Sysmex the ideal partner for the
next development phase,” comments Prof. Hartmut Juhl, CEO of Indivumed and Inostics.

“With Sysmex, we expect achieving our goal to make Inostics technology the leading
approach for DNA-based cancer diagnostics for the worldwide benefit of cancer patients.
The fact that Sysmex has its European Headquarter in the Hamburg area facilitates a smooth
transition and an undelayed continuation of Inostics business” says Dr. Frank Diehl,
co-founder of Inostics, who continues to work for Inostics as Chief Scientific Officer and
Managing Director.

Following the closing of the transaction, Indivumed will independently expand its
tissue-based clinical research service business leveraging a comprehensive and very high
quality tumor-biobank and its well-established prowess in the analysis of proteins and
cancer pathways for drug development and patient diagnostics.

JMP Securities LLC acted as financial advisor and Freshfields Bruckhaus Deringer LLP
served as legal counsel to Inostics and its shareholder in the transaction.

About Indivumed GmbH

Indivumed GmbH, a privately hold biotech company, was founded 2002 in Hamburg,
Germany, to promote the development and clinical implementation of individual cancer
therapies. Based on a highly standardized tumor biobank and a unique clinical
infrastructure with clinical partners in Germany and the US, Indivumed offers a broad
range of specialized research services to biopharmaceutical companies and academia and
performs biomarker research and development. With its subsidiary IndivuTest GmbH,
Indivumed provides high-quality-tissue based tumor analysis to patients and started an
initiative with oncologists in Germany and the US to improve personalized cancer therapy
strategies in the clinical routine.

For more information (also about Inostics and IndivuTest) please visit


About Sysmex Corporation

Sysmex Corporation (Headquarter: Kobe, Japan), a listed company at the Tokyo Stock
Exchange market, supports human health. Sysmex is an integrated company, developing and
manufacturing the instruments, reagents and software that are needed for in-vitro
diagnostics, and providing the necessary sales and support networks. Sysmex is expanding
operations, augmenting traditional strength in hematology with non-hematology fields such
as immunochemistry and hemostasis, as well as the life science field. Sysmex is leveraging
its proprietary technologies to create new testing and diagnostic technologies that aim to
ensure optimal healthcare for all.

For more information please visit http://www.sysmex.com.

        Press contact:
        Swantje Niphut
        E-Mail: press@indivumed.com
        Phone: +49(0)40-413383-0

SOURCE Indivumed GmbH

Source: PR Newswire