At Six Months Post-Launch, Nearly Two Thirds of Surveyed U.S. Medical Oncologists Have Prescribed Xofigo to Their Prostate Cancer Patients

February 5, 2014

The Majority of Current Non-Prescribers Anticipate Prescribing Xofigo within the Next Year, According to Findings from Decision Resources Group

BURLINGTON, Mass., Feb. 5, 2014 /PRNewswire/ — Decision Resources Group finds that at six month post-launch in the United States, approximately two-thirds of surveyed U.S. medical oncologists have prescribed Algeta/Bayer HealthCare’s alpha-emitting radiopharmaceutical Xofigo. The majority of current non-prescribers indicated that they expect to prescribe Xofigo to their metastatic castrate-resistant prostate cancer (mCRPC) patients within the next year. Notably, a significantly higher percentage of medical oncologists surveyed at six months post-launch express a high willingness to prescribe Xofigo compared with at one month post-launch.

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Other key findings from the second wave of the LaunchTrends(®) Xofigo report:

    --  One of the main perceived advantages of Xofigo for the treatment of
        mCRPC over Johnson & Johnson/Janssen Biotech/Janssen-Cilag's Zytiga and
        Medivation/Astellas Pharma's Xtandi lie in its bone-targeted mechanism
        of action.
    --  Xofigo's efficacy benefit and its safety profile are also cited among
        the agent's top perceived advantages, according to surveyed medical
    --  Half of surveyed medical oncologists who have prescribed Xofigo for
        docetaxel-naive symptomatic mCRPC indicated high satisfaction with the
        agent; one-quarter of prescribers indicated that it is too soon to draw
    --  Xofigo is perceived by surveyed medical oncologists to outperform other
        agents on the attributes of pain palliation, delaying time to
        symptomatic skeletal event, reducing the need for bisphosphonates,
        supportive and palliative care.
    --  Among treatment-associated side effects, bone marrow failure, the
        incidence of hematologic toxicity and the uncertainty over long-term
        safety are most commonly perceived to be of greater concern with Xofigo
        compared with other agents used to treat symptomatic mCRPC.

Comments from Decision Resources Group Senior Director Rachel Webster, D.Phil., M.Sc.:

    --  "The need for Xofigo to be administered in a nuclear medicine facility
        is regarded as the top disadvantage over to Zytiga and Xtandi for the
        treatment of docetaxel-naive and docetaxel-pretreated mCRPC."
    --  "However, when considering the potential prescribing constraints,
        surveyed medical oncologists weight more highly the lack of familiarity
        with Xofigo and its cost over the need to administer this agent in a
        specialist nuclear medicine facility."

Additional Resources:

    --  Members of the media are welcome to attend our upcoming webinar based on
        this report entitled Tracking the Trial, Adoption and Usage of Xofigo.
        This presentation will be held on Tuesday, February 18, 2014. For more
        information, please contact Christopher Comfort at

About Decision Resources Group

Decision Resources Group is a cohesive portfolio of companies that offers best-in-class, high-value information and insights on important sectors of the healthcare industry. Clients rely on this analysis and data to make informed decisions. Please visit Decision Resources Group at www.DecisionResourcesGroup.com.

All company, brand, or product names contained in this document may be trademarks or registered trademarks of their respective holders.

For more information, contact:

Decision Resources Group

Christopher Comfort



SOURCE Decision Resources Group

Source: PR Newswire

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