June 18, 2014
Role Reversal: Linking A Reproductive Pathway To Obesity
People and mice with mutations in a specific signaling pathway, known as kisspeptin, suffer reproductive effects such as delayed puberty and infertility. Research of this pathway has focused on its role in reproduction, but a June 17 study in the Journal of Clinical Investigation looked at its effects on metabolism.
The results of this study have potential to translate into approaches to treat human obesity.