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Drug Reduces Cocaine-Seeking Behavior

Posted on: Thursday, 8 November 2007, 15:00 CST

U.S. government scientists have provided further evidence that a drug known as D-cycloserine helps extinguish the craving behaviors of drug addiction.

Scientists at the U.S. Department of Energy's Brookhaven National Laboratory found mice treated with D-cycloserine were less likely to spend time in areas where they had been trained to expect cocaine than were mice treated with a placebo.

Since the association between drugs and the places where they are used can trigger craving and-or relapse in humans, a medication that could aid in the reduction or even extinction of such responses could be a powerful tool in the treatment of addiction, said Carlos Bermeo, a Stony Brook University graduate student working under the direction of Brookhaven neuroscientist Panayotis Thanos.

Bermeo presented the study this week in San Diego during the annual meeting of the Society for Neuroscience.


Source: United Press International

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