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Exact Sciences Diagnostic Technology Found Effective in Detection of Cancer

Posted on: Friday, 16 November 2007, 12:00 CST

Exact Sciences has reported that the final results of the prospective, blinded, multi-center study of its version 2 technology for stool-based DNA screening for colorectal cancer were statistically consistent with the interim findings published earlier.

This study evaluated stool-based DNA (sDNA) in 82 patients with colorectal cancer and 363 colonoscopically normal individuals using Exact's version 2 technology. The study results were statistically consistent with the interim results and demonstrated 83% sensitivity for detecting cancers with a specificity of 82%. The interim study results from the first 40 cancer patients and 122 normal individuals reported 88% sDNA sensitivity for detecting cancer with a specificity of 82%.

Jeffrey Luber, president of Exact Sciences, said: "We are excited that these results are within the sensitivity range that was expected and we believe that they provide important validation of our version 2 technology."


Source: Datamonitor

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