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Last updated on May 28, 2012 at 18:09 EDT

Expectant and Pregnant Mothers: Get Your Neck Checked

January 2, 2008
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Pregnancy can be an exciting, joyous and rewarding time for a woman. It is also the time a thyroid condition may surface or become more difficult to control in an expecting or pregnant mother.

January is Thyroid Awareness Month, and the American Association of Clinical Endocrinologists (AACE) are encouraging women who are considering pregnancy or are already pregnant to have their thyroid checked. Doing so can help ensure the safe delivery of a healthy child.

“Although many thyroid disorders that affect pregnancy can be treated easily, early detection is critical,” AACE President Richard Hellman MD, FACP, FACE said. “Even before conception, an untreated thyroid may encumber a woman’s ability become pregnant or even lead to a miscarriage.”

The thyroid is a small, butterfly-shaped gland that makes thyroid hormone which affects the function of many of the body’s organs including the heart, brain, liver, kidneys and skin. A malfunctioning thyroid that has gone unnoticed and untreated in a woman’s body can be dangerous for her and the child.

“It’s certainly something to consult with an endocrinologist about,” Hellman said. “As experts on the thyroid, we are able to treat women with a thyroid condition and help them to deliver a happy and healthy child.”

AACE, in observance of January’s Thyroid Awareness Month: “Treating Your Thyroid: It Deserves the Best Care,” has developed an important list of “Things Every Mother Should Know” that is critical for the health of a newborn child. More information is available at www.thyroidawareness.com.

Importance of adequate iodine intake in pregnancy

 —  Thyroid hormone is necessary for normal brain development. In early     pregnancy, babies get thyroid hormone from their mothers. Later on as the     baby’s thyroid develops it makes its own thyroid hormone. An adequate     amount of iodine is needed to produce fetal and maternal thyroid hormone.     The best way to ensure adequate amounts of iodine reach the unborn child is     for the mother to take a prenatal vitamin with a sufficient amount of     iodine. Not all prenatal vitamins contain iodine, so be sure to check     labels properly.      

Hyperthyroidism & pregnancy

 —  Hyperthyroidism, if untreated, can lead to stillbirth, premature     birth, or low birth weight for the baby. Sometimes it leads to fetal     tachycardia, which is an abnormally fast pulse in the fetus. Women with     Graves’ disease have antibodies that stimulate their thyroid gland. These     antibodies can cross the placenta and stimulate a baby’s thyroid gland. If     antibody levels are high enough, the baby could develop fetal     hyperthyroidism, or neonatal hyperthyroidism.          A woman with hyperthyroidism while pregnant puts her at an increased risk     for experiencing any of the signs and symptoms of hyperthyroidism. And     unless the condition is mild, if it is not treated promptly a woman could     miscarry during the first trimester; develop congestive heart failure,     preeclampsia, or anemia; and, rarely, develop a severe form of     hyperthyroidism called thyroid storm, which can be life threatening.      

Hypothyroidism & pregnancy

 —  Thyroid hormone is critical for the brain development of a fetus,     because it depends solely on its mother for its thyroid hormone for most of     the first trimester of pregnancy. When deprived of thyroid hormone, a baby     is at an increased risk for neural development, which may lead to mental     retardation.          Most women who develop hypothyroidism during pregnancy have mild disease     and may experience only mild symptoms or sometimes no symptoms. However,     having a mild, undiagnosed condition before becoming pregnant may worsen a     woman’s condition. A range of signs and symptoms may be experienced, but it     is important to be aware that these can be easily written off as normal     features of pregnancy. Untreated hypothyroidism, even a mild version, may     contribute to pregnancy complications. Treatment with sufficient amounts of     thyroid hormone replacement significantly reduces the risk for developing     pregnancy complications associated with hypothyroidism.      

Miscarriage and thyroid disorders

 —  A woman with untreated hypothyroidism is at the greatest risk for a     miscarriage during her first trimester. Unless the case is mild, women with     untreated hyperthyroidism may miscarry during the first trimester.      

Care of a child with congenital hypothyroidism

 —  All newborns in the United States are routinely tested for congenital     hypothyroidism. Children with this condition are deficient in thyroid     hormone, which is critical for the development of the nervous system.     Untreated, congenital hypothyroidism can lead to mental retardation and     stunted growth. Thanks to testing, every child born with congenital     hypothyroidism is promptly treated with thyroid hormone, allowing them to     develop normally and go on to live a normal, healthy life.      

For those taking thyroid hormone, what to do before becoming pregnant

How much and which thyroid hormone to take before conception

 —  Levothyroxine sodium pills are completely safe for use during     pregnancy. They are prescribed in dosages aimed at replacing the thyroid     hormone the thyroid isn’t making.  Once a woman begins taking this     medication, she will be monitored to ensure TSH levels have normalized.     After normalization, a doctor will want to check these levels every six to     eight weeks until normalization and less frequently thereafter. They may     also counsel women to take thyroid hormone pills at least one-half hour to     one hour before or at least three hours after taking iron-containing     prenatal vitamins or calcium supplements, which can interfere with the     absorption of thyroid hormone.          High levels of thyroxine (T4) appear to be required for normal brain     development early in the pregnancy. A combination of T4 and T3     (triodothyronine) as well as desiccated thyroid hormone do not provide     an adequate amount of T4 and therefore should be avoided in a woman     planning pregnancy or a woman that is already pregnant.      

How to achieve and maintain excellent control throughout pregnancy

 —  For a woman being treated for hypothyroidism, it’s imperative to have     her thyroid checked as soon as the pregnancy is detected so that medication     levels may be adjusted. TSH levels may be checked one to two weeks after     the initial dose adjustment to be sure it’s normalizing. Once the TSH     levels drop, less frequent check-ups are necessary during the pregnancy, as     they tend to stabilize by the middle of pregnancy. Although thyroid hormone     requirements are likely to increase throughout the pregnancy they tend to     eventually stabilize by the middle of pregnancy. The goal is to keep TSH     levels within normal ranges which are somewhat different than proper levels     in a non-pregnant woman. After giving birth, the doctor should adjust     dosage to the preconception level.      

Role of the endocrinologist

 —  An endocrinologist is a physician or medical scientist who researches     and treats patients with diseases relating to the endocrine system. Their     advanced and specialized training make them experts in the care of     endocrine disease, such as thyroid disorders.      

In an effort to educate expecting mothers and those that suspect they may suffer from a thyroid condition, AACE has developed ways for people to seek out additional information. The website, www.thyroidawareness.com, is a resource dedicated entirely to good thyroid health. Patient handouts covering hypothyroidism, hyperthyroidism, Hashimoto’s thyroiditis, thyroid nodules, thyroid cancer, radioiodine therapy, the thyroid, pregnancy and infancy are available in the offices of AACE endocrinologists.

For more information on the thyroid and the AACE Thyroid Awareness Month campaign, visit: www.thyroidawareness.com.

About AACE

AACE is a professional medical organization with nearly 6,000 members in the United States and 85 other countries. Founded in 1991, AACE is dedicated to the optimal care of patients with endocrine problems. AACE Clinical Endocrinologists advanced, specialized training enable them to be experts in the care of endocrine disease, such as diabetes, thyroid disorders, growth hormone deficiency, osteoporosis, cholesterol disorders, hypertension and obesity. For further information about AACE visit www.aace.com. For more information about the AACE Thyroid Awareness Month, visit www.thyroidawareness.com.

About ATA

Founded in 1923, the ATA is a professional society of 900 U.S. and international physicians and scientists who specialize in the research and treatment of thyroid diseases. The ATA is the North American professional society for physicians and researchers specializing in diseases of the thyroid gland. The ATA promotes excellence and innovation in clinical care, research, education, and public advocacy.

Thyroid Awareness Month is sponsored by AACE and supported through an unrestricted educational grant from Abbott Laboratories.

 Contact: American Association of Clinical Endocrinologists Bryan Campbell Email Contact  Greg Willis Email Contact  904-353-7878  

SOURCE: American Association of Clinical Endocrinologists