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CV Therapeutics's Ranexa Reduces Chest Pain in Angina Patients

Posted on: Wednesday, 2 April 2008, 09:01 CDT

CV Therapeutics has reported that Ranexa significantly reduced the risk of recurrent ischemia, worsening angina and intensification of antianginal therapy, in angina patients in the Merlin-Timi 36 study.

Additionally, Ranexa has significantly improved all measures of exercise performance compared to placebo, including reductions in the time to onset of angina (p=0.002) and time to the onset of 1mm ST segment depression (p=0.002), a signal of ischemia, in these Merlin-Timi 36 angina patients.

David Morrow, lead investigator of the Merlin-Timi 36 study, said: "This new subgroup analysis shows consistent safety and efficacy across a broader group of angina patients than those studied previously and reaffirms ranolazine as an option for treating chronic angina."


Source: Datamonitor

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