July 7, 2008
Study Uncovers Process Involved in Cancer
U.S. and Israeli medical researchers say they have discovered one of the factors involved in mitosis -- the ability of cells to daily divide and replicate.
Since an inability to control mitosis is one of the hallmarks of cancer, the discovery by researchers at the Fox Chase Cancer Center in Philadelphia and the Technion-Israel Institute of Technology in Haifa, Israel, might help increase the efficiency of cancer drugs that disrupt DNA replication, such as gemcitabine, or drugs that prevent mitosis, like paclitaxel.
The study led by Tim Yen of Fox Chase and Avram Hershko of Technion appears in the Proceedings of the National Academy of Sciences.