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Express Scripts Second Quarter 2008 Earnings Conference Call

July 9, 2008

Express Scripts (NASDAQ:ESRX), one of the largest pharmacy benefit management companies in North America, announced today its intention to release its second quarter earnings on Wednesday, July 30, 2008 after the market closes and will hold its quarterly conference call to discuss second quarter results on Thursday, July 31, 2008, at 10:00 a.m. Eastern Time (9:00 a.m. Central Time).

This call is being webcast and can be accessed at Express Scripts Web site at www.express-scripts.com

Express Scripts, Inc. is one of the largest PBM companies in North America, providing PBM services to thousands of client groups, including managed-care organizations, insurance carriers, employers, third-party administrators, public sector, workers compensation, and union-sponsored benefit plans.

Express Scripts provides integrated PBM services, including network-pharmacy claims processing, home delivery services, benefit-design consultation, drug-utilization review, formulary management, and medical-and drug-data analysis services. The Company also distributes a full range of biopharmaceutical products directly to patients or their physicians, and provides extensive cost-management and patient-care services.

Express Scripts is headquartered in St. Louis, Missouri. More information can be found at http://www.express-scripts.com, which includes expanded investor information and resources.




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