July 16, 2008

Interventional Spine Trains Its 400th Physician on Its Percutaneous Technology for Back Pain Treatment

Interventional Spine, Inc. today announced that it has surpassed the 400-physician milestone in delivering training on its PERCUTANEOUS spine therapy technologies since introducing its product line less than two years ago. Of this group, 150 physicians have completed such training in the past six months, illustrating the increasing pace at which the company is expanding its presence in the spine treatment market.

"This performance and achievement is indicative of the accelerating interest by physicians in being able to offer their patients treatment alternatives with Interventional Spine's products, which are aimed at eliminating open back surgery when conservative care fails to mitigate chronic, debilitating back pain," said Walter A. Cuevas, the Company's CEO.

"Founded on patented technologies and focused on PERCUTANEOUS back pain treatment options, Interventional Spine's products improve and expand the continuum of care available to patients. Together with physicians worldwide, we are helping to reduce the trauma of `open' fusion surgeries performed nearly 500,000 times a year in the U.S. alone. All of our employees believe in the goal of delivering improved medical outcomes at lower overall costs to patients and healthcare systems worldwide. Real change is happening in the treatment of back pain and Interventional Spine is thrilled to be part of it," Mr. Cuevas added.

"Training milestones such as what Interventional Spine has achieved are possible only with the dedicated help of our physician faculty members, who are willing to share their clinical knowledge and experience with their peers and with our Clinical Specialists who work with these physicians. We are grateful to have such dedicated individuals, and this announcement is a public expression of our thanks," Mr. Cuevas concluded.

Interventional Spine, Inc. is a privately held company based in Irvine, California that designs, develops, and markets patented implantable devices for the spine that can be deployed via percutaneous techniques, supported by the Company's unique product introduction systems, providing benefits to patients, surgeons, and hospitals. More information on the Company and its products can be found at: www.i-spineinc.com.