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CAS Medical Systems, Inc. Announces the Sale and Installation of FORE-SIGHT Absolute Cerebral Oximeters At Children’s Hospital Boston

September 22, 2008

BRANFORD, Conn., Sept. 22, 2008 (GLOBE NEWSWIRE) — CAS Medical Systems, Inc. (Nasdaq:CASM), today announced the sale and installation of four of its FORE-SIGHT(r) Absolute Cerebral Oximeters to Children’s Hospital Boston. Children’s Hospital has been listed as the top pediatric hospital in the country for heart and heart surgery, according to U.S. News and World Report’s “America’s Best Children’s Hospitals” issue, dated June 9, 2008. The FORE-SIGHT monitors purchased by Children’s Hospital Boston are to be used primarily on their critical cardiac care patients before, during and after surgery in the Cardiac ICU, Cardiac OR and Cardiac Catheterization Lab settings.

Dr. Francis McGowan, Chief of Cardiac Anesthesiology at Children’s Hospital Boston, stated, “We are pleased with the scientifically-driven approach taken and support that we have received from the CASMED research team over the past several months.”

Children’s Hospital Boston is a 397-bed comprehensive center for pediatric health care, offering a complete range of health care services for children. Since the U.S. News and World Report began rating hospitals 19 years ago, Children’s has always been regarded as one of the top two pediatric hospitals in the country. This year, Children’s is ranked second nationally and remains the number one pediatric hospital in New England, as well as the number one pediatric hospital in the country for heart and heart surgery. Each year, the Pediatric Cardiac Surgery Program provides surgical care to approximately 1,100 patients, with extraordinary success rates.

Andrew E. Kersey, President and CEO of CASMED, stated, “We are pleased to complete this important sale of our FORE-SIGHT monitors to Children’s Hospital Boston so shortly after launch of our neonatal/infant product. We have developed strong relationships at this world class hospital, and we applaud the staff at the hospital for their continued commitment to patient care, quality and vision as demonstrated by their outstanding track record. We are looking forward to reporting additional successes with FORE-SIGHT in this market.”

About CASMED(r) – Monitoring What’s Vital

CAS Medical Systems, Inc. is a leading developer and manufacturer of medical devices for non-invasive patient monitoring. The Company’s FORE-SIGHT Absolute Cerebral Oximeter is the only cerebral oximeter available with FDA clearance for non-invasive, continuous measurement of absolute cerebral tissue oxygen saturation for neonates, infants, children and adults. This information helps avert brain damage or death during surgery and in critical care situations by allowing clinicians to identify patients with dangerously low levels of cerebral oxygen and intervene to reverse the condition.

The Company’s product lines include the high-acuity monitoring capabilities of the FORE-SIGHT Cerebral Oximeter, the bedside patient monitoring line of vital signs and cardio-respiratory monitoring products, proprietary non-invasive blood pressure measurement technology, and supplies and service including blood pressure cuffs and products for neonatal intensive care. CASMED products are designed to meet the needs of a full spectrum of patient populations worldwide, ranging from adults to pediatrics and neonates.

For further information regarding CAS Medical Systems, Inc., visit the Company’s website at www.casmed.com.

The CAS Medical Systems, Inc. logo is available at http://www.globenewswire.com/newsroom/prs/?pkgid=4675

Statements included in this press release, which are not historical in nature, are forward-looking statements made pursuant to the safe harbor provisions of the Private Securities Litigation Reform Act of 1995. Statements relating to the future financial performance of the Company are subject to many factors including, but not limited to, the customer acceptance of the products in the market, the introduction of competitive products and product development, commercialization and technological difficulties, the impact of actions and events involving key customers and vendors, and other risks detailed in the Company’s Form 10-K for the year ended December 31, 2007 and other subsequent Securities and Exchange Commission filings.

Such statements are based upon the current beliefs and expectations of the Company’s management and are subject to significant risks and uncertainties. Actual results may differ from those set forth in the forward-looking statements. When used in this press release the terms “anticipate”, “believe”, “estimate”, “expect”, “may”, “objective”, “plan”, “possible”, “potential”, “project”, “will” and similar expressions identify forward-looking statements. The forward-looking statements contained in this press release are made as of the date hereof, and we do not undertake any obligation to update any forward-looking statements, whether as a result of future events, new information or otherwise.

This news release was distributed by GlobeNewswire, www.globenewswire.com

 CONTACT:  CAS Medical Systems, Inc.           Susan Carron, Director of Corporate Communications           203-488-6056           ir@casmed.com 



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