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Three Genes Identified in Gout

Posted on: Tuesday, 7 October 2008, 15:15 CDT

U.S. and Dutch scientists have identified two genes and confirmed the role of a third in the creation of uric acid in gout, a painful form of arthritis.

The researchers from the U.S. National Institutes of Health and the Netherlands Organization for Scientific Research found the three genetic variations were associated with up to a 40-fold increased risk in developing gout.

The researchers said their findings suggest genetic testing might one day be used to identify individuals at risk for gout before symptoms develop, as well as in determining who might benefit from medications to prevent the development of gout.

The study was reported in the Sept. 30 online edition of The Lancet.


Source: United Press International

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