November 6, 2008
Rheumatologists Anticipate Using Orencia and Rituxan More Frequently in First- and Second-Line Therapy for the Treatment of Rheumatoid Arthritis
WALTHAM, Mass., Nov. 6 /PRNewswire/ -- Decision Resources, one of the world's leading research and advisory firms focusing on pharmaceutical and healthcare issues, finds that surveyed U.S. rheumatologists anticipate using Bristol-Myers Squibb's Orencia and Biogen Idec/Genentech/ Chugai/Zenyaku Kogyo's Rituxan, also marketed as Roche's MabThera, more frequently in first- and second-line biologic therapy through 2010 for the treatment of rheumatoid arthritis.
"Currently, surveyed rheumatologists prescribe Orencia in earlier lines of therapy than Rituxan - 78 percent of them most commonly prescribe Orencia as a third-line biologic, whereas 51 percent of them use Rituxan as a fourth-line biologic," stated Madhuri Borde, Ph.D., analyst at Decision Resources. "Surveyed rheumatologists contend that physician familiarity, concern about the long-term effects of B-cell depletion with Rituxan and preference for Orencia's mechanism of action influences physicians to prescribe Orencia instead of Rituxan."
"All three TNF-alpha inhibitors are vying for first-line biologic use," added Dr. Borde. "However, our current analysis of patient-level claims data shows a much wider disparity than we observed in our 2007 report in the percentage of patients who had received another TNF-alpha inhibitor in the line of treatment preceding Enbrel versus those patients starting either Humira or Remicade as a non first-line drug."
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For more information, contact: Natalia Morales Elizabeth Marshall Decision Resources Decision Resources, Inc. 781-296-2691 781-296-2563 [email protected] [email protected]
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