Thiamine reverses diabetic kidney disease
Posted on: Tuesday, 9 December 2008, 18:06 CST
Researchers in Britain and Pakistan say high doses of thiamine, or vitamin B1, can reverse the onset of early diabetic kidney disease.
Dr. Naila Rabbani and Paul J. Thornalley at Warwick Medical School at the University of Warwick, in collaboration with researchers at the University of Punjab and Sheik Zaid Hospital in Lahore, Pakistan, say that taking high oral doses of thiamine can dramatically decrease the excretion of albumin and reverse early stage kidney disease in type 2 diabetes patients.
The study, published online in the journal Diabetologia, shows 300 mg of thiamine taken orally each day for three months reduced the rate of albumin excretion in type 2 diabetes patients. The albumin excretion rate was decreased by 41 percent from the value at the start of the study. The results also showed 35 percent of patients with microalbuminuria saw a return to normal urinary albumin excretion after being treated with thiamine.
Forty patients with type 2 diabetes ages 35-65 were randomly assigned a placebo or three doses of 100mg tablets of thiamine a day for three months.
The Warwick research team showed that thiamine deficiency could be key to a range of vascular problems for diabetes patients.
Source: United Press International
Related Articles
- Lipitor 80 Mg Reduced the Risk of Heart Attack and Stroke in Patients With Heart Disease, Type 2 Diabetes and Chronic Kidney Disease
- Pacgen Completes Patient Recruitment for Phase II Dose Ranging Trial of Novel Anti-Fungal Drug
- GlaxoSmithKline Responds to JAMA Article on the ICES Thiazolidinediones and Cardiovascular Outcomes in Older Patients With Diabetes
- Synvista Announces New Data Showing Haptoglobin Type Predicts Effectiveness of Tight Glycemic Control on Cardiovascular Outcomes in Patients With Diabetes
- Association of Ischemia on Stress ^Sup 99m^Tc-Tetrofosmin Myocardial Perfusion Imaging With All-Cause Mortality in Patients With Diabetes Mellitus
- Study Shows New Compound May Reduce Risk of Vision Loss in Patients With Diabetes
- Noninvasive Diagnosis of Coronary Artery Disease in Patients With Diabetes By Dobutamine Stress Real-Time Myocardial Contrast Perfusion Imaging
- New Data Analysis Shows Patients With Diabetes Taking Pfizer's Lipitor(R) Experienced Major Reductions in Heart Attack and Stroke
- Effects of Metformin and Rosiglitazone Treatment on Insulin Signaling and Glucose Uptake in Patients With Newly Diagnosed Type 2 Diabetes: A Randomized Controlled Study
- Study Shows Impact of Coreg(R) (Carvedilol) on Cardiovascular Risk Factors in Patients With Diabetes and Hypertension
 |
 |
User Comments (0)
RSS Feeds