Oridion Announces Significant Medical Studies Presented at STA

JERUSALEM and NEEDHAM, Massachusetts, February 2 /PRNewswire-FirstCall/
– Oridion Systems Ltd. (SIX Swiss Exchange: ORIDN). During the recent annual
meeting of the Society for Technology in Anesthesia (STA) San Antonio, Texas,
major new findings from numerous medical research projects demonstrating the
clinical benefit of end-tidal CO2 (EtCO2) monitoring using Microstream(R)
capnography technology were presented.

Research was presented on the new Oridion technology Integrated Pulmonary
Index(TM), which utilizes end-tidal carbon dioxide (EtC02), Respiratory Rate,
Pulse Rate and oxygen saturation (SpO2) to provide a clear inclusive
assessment of a patient’s ventilatory status. A study conducted by David
Gozal, MD from Hadassah University Hospital and Yaacov Gozal, MD from Shaare
Zedek Medical Center, both in Jerusalem, on the validity and application of
the Integrated Pulmonary Index(TM) in the pediatric population, concluded
that it would be “particularly useful for non-expert personnel monitoring
patients undergoing procedures requiring sedation or recovering from them”.
An additional study carried out by Dr Yaacov Gozal on the reliability of this
new software postoperatively concluded that since the Integrated Pulmonary
Index(TM) (510K pending) is displayed as a single value, “it may simplify the
monitoring of patients in a busy PACU.”

Several studies were also presented showing the unique Oridion family of
CO2 breath sampling lines – FilterLine(R), and how they bring the superior
Microstream(R) measuring technology to all patients in all settings. A study
by Paul F. Nuccio, RRT and Michael R. Jackson, RRT-NPS from The Brigham and
Woman’s Hospital in Boston on EtCO2 measurements with non-invasive
ventilation (NIV), demonstrated that the oral/nasal Smart CapnoLine(R) H Plus
CO2 sampling line “proved to be the most reliable” method “in trending EtCO2
with different ventilator settings and leak rates in the normal subject.”

The advantage of the Smart CapnoLine(R) H Plus O2 in sleep diagnostics
was demonstrated by Peter L. Whitesell MD et al. This study showed that only
the Oridion Smart CapnoLine(R) H Plus O2 met the “test objective of detecting
changes associated with apnea and hypopnea”, and that it was “superior to
other CO2 sampling lines, as it did not miss events”.

Benefits of another Oridion sampling line were shown in a study comparing
CO2 sampling lines, which concluded that the Oridion Smart CapnoLine(R) Plus
O2 “proved to be effective for EtCO2 sampling, providing accurate readings
compared to other tested CO2 sampling lines with and without oxygen supply,
when sampling from nose and mouth breathers”.

In an interesting application, the use of capnography on endangered
animals was presented as well. A comprehensive research study conducted by

Robin W. Radcliffe, DVM from Cornell University and others on the effect
postural changes had on EtCO2 readings in the endangered African black
rhinoceros and its importance to field anesthesia, concluded that EtCO2
monitoring could provide “important new information to enhance
decision-making at this hazardous time [during anesthesia],” and that the
results of the study “may be of interest in humans and their physiologic
response to position [when sedated].”

“We are very pleased with the broad application of our products in
research,” said Gerry Feldman, president of Oridion. “The studies presented
at STA demonstrate the value of measuring end-tidal carbon dioxide to monitor
ventilation as well as the importance of the FilterLine(R) CO2 sampling line
by which exhaled gas is collected from the patient. We are further excited
over the results of our Integrated Pulmonary Index from Israel. The new index
is described in these reports as providing a simple and clinically useful
approach to assessing the interactions of heart rate, oxygen saturation,
respiratory rate and adequacy of ventilation.”

Oridion is the global leader of innovative capnography monitoring
solutions helping to improve patient safety and its Microstream(R)
capnography technology is the standard of care in ventilation monitoring.

A full list of the aforementioned studies presented at STA can be found
on the Oridion website:

http://www.oridion.com/global/english/clinical_solutions/overview/

research.html

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this hyperlink into your Internet browser’s URL address field. Remove the
space if one exists.)

About Oridion

Oridion Systems Ltd. (http://www.oridion.comwww.oridion.com) is a global
medical device company specializing in patient safety monitoring. The Company
operates through wholly owned subsidiaries in the United States, Europe, and
Israel.

Oridion develops proprietary medical devices and patient interfaces,
based on its patented Microstream(R) technologies, for the enhancement of
patient safety through the monitoring of the carbon dioxide (CO2) in a
patient’s breath. These products provide effective, proven airway management
and are used in various clinical environments, including procedural sedation,
pain management, operating rooms, critical care units, post-anesthesia care
units, emergency medical services, transport, alternate care and other
settings where patients’ ventilation may be compromised and at risk.

Certain statements made herein that are not historical are
forward-looking within the meaning of the Private Securities Litigation
Reform Act of 1995. The words “estimate” “project” “intend” “expect”
“believe” and similar expressions are intended to identify forward-looking
statements. These forward-looking statements involve known and unknown risks
and uncertainties. Many factors could cause the actual results, performance
or achievements of the Company to be materially different from any future
results, performance or achievements that may be expressed or implied by such
forward-looking statements, including, among others, our ability to maintain
profits, the market demands for our Capnography products, our ability to
focus our team on the Capnography business, changes in general economic and
business conditions, inability to maintain market acceptance to the Company’s
products, inability to timely develop and introduce new technologies,
products and applications, rapid changes in the market for the Company’s
products, loss of market share and pressure on prices resulting from
competition, introduction of competing products by other companies, inability
to manage growth and expansion, loss of key OEM partners, inability to
attract and retain qualified personnel, inability to protect the Company’s
proprietary technology.

Furthermore, this press release does not constitute an offer to sell or a
solicitation of an offer to buy any securities. The Company’s shares issued
have not been, and will not be, registered under the US Securities Act of
1933, as amended (the “Securities Act”), or under any of the relevant
Securities Laws of any state of the United States. The Company’s shares may
not be offered, sold or delivered, directly or indirectly, to, or for, the
account of any US person (as defined in regulation S under the Securities
Act) in or into the United States, or by use of the US mail, or by any means
or instrumentality of United States interstate commerce, absent registration,
or an exemption from registration under the Securities Act.

    For further Oridion information please contact
    Alan Adler, Chairman and Chief Executive Officer
    Walter Tabachnik, Chief Financial Officer
    Elena Gerberg, Investor Relations
    e-mail: investor@oridion.com
    website: http://www.oridion.com
    phone: +972-2-589-9159
    address: Oridion Systems Ltd., P.O. Box 45025, 91450 Jerusalem, Israel

SOURCE Oridion Systems Ltd.