March 20, 2009
Chronic Cannabis Use Causes Severe Vomiting Sickness
This obscure clinical manifestation of severe vomiting sickness due to chronic abuse of marijuana, recognized by Dr. Sontineni and his colleagues at the Creighton University of Omaha, NE, was published on March 14, 2009 World Journal of Gastroenterology.
Recent research into the neurobiology of cannabis has led to the identification of different receptor types including two specific types that mediate neuropsychiatric and immunologic effects.
The syndrome was first recognized in Australia around the Adelaide hills. The exact mechanism leading to generation of these symptoms, why it appears only after several years of marijuana abuse and why compulsive hot showering behavior relieves the symptoms is still under scientific investigation.
The recognition of this novel syndrome and increasing physician awareness is supported by the Department of Medicine at Creighton University Medical Center. Similarly, scientists and doctors at other institutions worldwide are beginning to identify more cases with this new syndrome as a result of chronic marijuana abuse among populations.
Reference: Sontineni SP, Chaudhary S, Sontineni V, Lanspa SJ. Cannabinoid hyperemesis syndrome: Clinical diagnosis of an under recognized manifestation of chronic cannabis abuse. World J Gastroenterol 2009; 15(10): 1264-1266 http://www.wjgnet.com/1007-9327/15/1264.asp
On the Net: