Symphony Medical Announces First Patient Successfully Treated With Novel Congestive Heart Failure Therapy
European Trials Commencing for Injectable Biopolymer to Repair Weakened Heart Wall
The Company intends to sponsor a clinical study of Algisyl-LVR at four centers in
Algisyl-LVR is an implantable medical device under clinical development intended to prevent or reverse the progression of congestive heart failure in patients who have an enlarged left ventricle. The procedure, which is performed on patients undergoing a planned cardiac surgery for mitral valve regurgitation or coronary artery disease, involves injecting a proprietary biopolymer directly into strategic locations of the heart’s left ventricle wall. As it is injected, the biopolymer thickens and forms firm, gel-like structures that remain in the heart muscle as permanent implants. These implants act to re-shape the heart, reduce the size of the dilated left ventricle and thicken the damaged wall of the heart, thus returning the heart to a healthier form that facilitates improved cardiac function and performance.
The first Algisyl-LVR patient was successfully treated by Prof. Dr.
Prof. Dr. Bauernschmitt said, “We are extremely pleased with the initial outcome of the first patient treatment with Algisyl-LVR. The administration of this implantable biopolymer to the heart wall provides a practical new tool to prevent and even reverse the dilation of the left ventricle, which is typical in congestive heart failure. As such, this new therapy has the potential to provide significant health benefits to a growing population of patients. While it is still very early, the initial outcome of Algisyl-LVR suggests that the therapy is feasible and safe while it provides immediate, tangible benefits. We look forward to treating additional patients here at the German Heart Center.”
About Symphony Medical, Inc.
Symphony Medical, founded in 2003, is a privately-held, venture-backed development stage company developing proprietary biotherapeutic products and tools to address the unmet clinical needs of millions of patients suffering from cardiac disorders. Headquartered in
The Company has two products in its late-stage development pipeline – Algisyl-LVR(R) for the treatment to prevent or reverse the progression of chronic heart failure (CHF) and mitral valve regurgitation (MR), conditions affecting well over 5 million Americans. Symphony’s approach involves implanting a space-occupying biocompatible polymer into strategic areas of the heart’s left ventricle (LV) wall to affect LV shape and prevent or reverse LV enlargement. Reshaping and thickening the LV wall reduces wall stress, reduces mitral valve regurgitation and provides lasting improvement of cardiac function with an associated improvement in the patient’s clinical status and quality of life. Algisyl-LVR has advanced to human clinical studies with a first-in-man study initiated in
For more information on Symphony Medical please visit our website at www.symphonymed.com.
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SOURCE Symphony, Medical Inc.