April 23, 2009
Genetic impulsivity predicts alcoholism
Genetic predisposition to impulsivity is a trait predictive of alcoholism, U.S. researchers report.
Nicholas Grahame of the Indiana University-Purdue University Indianapolis School of Science used selective breeding for 30 generations to produce mice that were high-volume alcohol drinkers and others that avoided consuming alcohol.
The study, published online ahead of print of the July issue of the journal Alcoholism: Clinical and Experimental Research, found the mice with high alcohol preferring genes were more impulsive than their low drinking counterparts -- demonstrating that predisposition to impulsivity is predictive of alcoholism.
Our data can clearly be extrapolated to humans and strongly suggests that impulsivity contributes to high alcohol drinking, Grahame said in a statement.
Consequently, the diagnosis of any disorder associated with impulsivity, such as attention deficit disorder or bipolar disorder, is cause for concern about future problems with alcoholism.