April 29, 2009
Drug for Inflammatory Breast Cancer
An oral medication could help some patients with inflammatory breast cancer.
Aggressive forms of inflammatory breast cancer can be difficult to treat, often unresponsive to chemotherapy, radiation or approved medications. For patients whose disease is resistant to anthracycline or taxane and trastuzumab treatment, options are limited. However, a new study of the oral growth inhibitor, lapatinib, showed promise for patients for which all other treatment options have failed.
"Lapatinib monotherapy is potentially clinically effective in heavily pretreated patients with inflammatory breast cancer with HER2+ tumors," study authors wrote. "The objective response rate noted...coupled with the median duration of response and median overall survival supports a role for lapatinib in these patients."
SOURCE: Lancet Oncology, 2009