Bayer to Present Data on Development Compound BAY 73-4506 at 45th Annual Meeting of the American Society of Clinical Oncology
“Bayer is committed to expanding our oncology franchise, and the oral multi-kinase inhibitor BAY 73-4506 is one of the promising compounds in the company’s pipeline,” said
The BAY 73-4506 data being presented are:
Phase I study of BAY 73-4506, an inhibitor of oncogenic and angiogenic kinases, in patients with advanced refractory colorectal carcinoma
Dirk Strumberg, MD, Department of Hematology and Medical Oncology, Marienhospital Herne, University Medical School of Bochum, Germany
- Abstract 3560, Poster,
Saturday, May 30, 2009, 8:00-11:00 a.m., Level 2, West Hall C
Phase II study of BAY 73-4506, a multikinase inhibitor, in previously untreated patients with metastatic or unresectable renal cell cancer
Tim Eisen, PhD, Addenbrooke’s Hospital and the University of Cambridge, UK
- Abstract 5033, Poster Discussion,
Friday, May 29, 2009, 2:00-6:00 p.m., Level 2, W230A
About BAY 73-4506 (DAST-Inhibitor)
BAY 73-4506 is a novel oral multi-kinase inhibitor with a kinase inhibition profile targeting angiogenic, stromal and oncogenic receptor tyrosine kinases (TK). BAY 73-4506 has been shown to inhibit tumor growth in preclinical models by hitting targets along a spectrum of angiogenic pathways, including VEGFR and TIE2. BAY 73-4506 has also been shown to prevent the proliferation of tumor cell lines while promoting apoptosis (cell death) by directly targeting several oncogenic TK receptors. The mechanism may offer promise to treat a broad spectrum of tumors.
About Bayer HealthCare Pharmaceuticals Inc.
Bayer HealthCare Pharmaceuticals Inc. is the U.S.-based pharmaceuticals unit of Bayer HealthCare LLC, a subsidiary of Bayer Corporation. One of the world’s leading, innovative companies in the healthcare and medical products industry, Bayer HealthCare combines the global activities of the Animal Health, Consumer Care, Diabetes Care, and Pharmaceuticals divisions. In the U.S., Bayer HealthCare Pharmaceuticals comprises the following business units: Diagnostic Imaging, General Medicine, Specialty Medicine and Women’s Healthcare. The company’s aim is to provide products that will improve human health worldwide by diagnosing, preventing and treating diseases.
Details on the studies can be found on the ASCO website: www.abstract.asco.org.
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SOURCE Bayer HealthCare Pharmaceuticals Inc.