Lab Uses Implanted Pig Cells To Fight Diabetes In Humans
Posted on: Thursday, 23 July 2009, 14:30 CDT
New Zealand-based biotech company Living Cell Technologies has launched an experiment that will place pig cells into eight volunteer participants.
Derived from piglets, the implanted cells create pig insulin, which contains similar properties to human insulin.
Researchers hope the trial will result in a noticeably lower blood sugar level and negate or delay the effects of Type 1 diabetes.
Professor Bob Elliott, medical director of LCT, said the cells were taken from pigs that lived in isolation on the Auckland Islands. The pigs have been bred in sterile locations in hopes of being free of diseases that could affect humans.
"LCT's pigs originate from the sub-Antarctic Auckland Islands and are disease free. The new unit ensures that they remain free of viruses, bacteria and parasites," he said.
Elliott told the Associated Press that even in the best case scenario, the treatment may not halt the symptoms, though he remains optimistic.
Other experts are fearful that the trial cold pose a new risk of introducing new diseases to humans.
Elliott told the AP that the risk of a pig endogenous retrovirus is “theoretical.”
"There is no evidence of a risk," he said.
"Nobody has developed a retrovirus."
Dr. Elliott has conducted two other trial procedures. One trial involved six volunteers in New Zealand during 1995 and 1996. The second trial involved Russian volunteers during July 2007.
Researchers noted that one of the volunteers from the New Zealand group began producing insulin 12 years after implantation. The other participants’ bodies rejected the pig cells, or the cells stopped producing insulin.
---
On the Net:
Source: redOrbit Staff & Wire Reports
Related Articles
- Oramed Pharmaceuticals Launches Phase 1A Trials of Its Insulin Suppository
- LCT Wins Approval to Initiate Phase I/IIa Diabetes Trial in New Zealand
- Living Cell Technologies Confirms Insulin Delivery From Implants in Diabetes Clinical Trial
- Oramed Completes Phase IB Trials of Oral Insulin Capsule
- Oramed Pharmaceuticals Successfully Completes Phase 1B Clinical Trials of Oral Insulin Capsule
- Diabetes Research Institute Invention Promotes Growth of Stem Cells into Insulin-Producing Cells
- Geron Scientists and Collaborators Differentiate Human Embryonic Stem Cells Into Insulin-Producing Islet-Like Clusters
- Brain Stem Cells Coaxed to Produce Insulin
- Insmed Receives European Orphan Drug Designation for SomatoKine for the Treatment of Extreme Insulin Resistance; Company to Initiate Clinial Trial in Type A Insulin Resistance
- Fla. Man Gets New Trial in Pig Stabbing
User Comments (0)


RSS Feeds