November 18, 2009
Unexplained Liver Hemorrhage After Metastasis Radiofrequency Ablation
Colorectal carcinoma is one of the most common cancers in the world. Approximately one in four of these patients have metastases at diagnosis, liver being the most common site involved. Although historically it was considered that liver metastases meant a very poor prognosis, today, due to improved systemic therapy, many patients will be candidates for local hepatic treatments such as surgery or less aggressive radiofrequency ablation. Both of these procedures have resulted in improvements in global and disease-free survival. However ,a report of unexplained liver haemorrhage after metastasis radiofrequency ablation has been published on October 28, 2009 in the World Journal of Gastroenterology.
Radiofrequency ablation is increasing used in the field of oncology. Although some studies have found low rates of complications, ranging from 2.4% to 8.9%, the rate of intraperitoneal haemorrhage is low (0.46%-1.6%) but relevant because this technique is increasingly used with few selection criteria for patients. The reported reasons for haemorrhage are usually related to mechanical injuries to the liver blood vessels and occur most often in patients with cirrhosis. Other cases have been attributed to serious coughing or hiccups after the radiofrequency treatment which might cause increased abdominal pressure and tumor rupture.
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