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Last updated on April 18, 2014 at 6:54 EDT

Treatment Of Helicobacter Pylori-negative Gastric MALT Lymphoma

May 9, 2010

Eradication of Helicobacter pylori (H. pylori) is a well-accepted initial therapy in cases of localized (stage ⓦ E) low-grade gastric mucosa-associated lymphoid tissue (MALT) lymphoma associated with H. pylori infection. However, there are no treatment guidelines for the management of H. pylori-negative low-grade gastric MALT lymphoma.

Retrospectively reviewing the clinical outcome and clinicopathologic factors of stage ⓦ E H. pylori-negative low-grade gastric MALT lymphoma cases from August 1998 to June 2009, a research team from South Korea analyzed the treatment outcome of H. pylori-negative low-grade gastric MALT lymphoma. Their study was published on May 7, 2010 in the World Journal of Gastroenterology .

Their results indicated that H. pylori eradication therapy may be an initial treatment option for localized H. pylori-negative gastric MALT lymphoma. Their study adds information which helps in the establishment of strategies for patients with localized H. pylori-negative gastric MALT lymphoma.

Reference: Park HS, Kim YJ, Yang WI, Suh CO, Lee YC. Treatment outcome of localized Helicobacter pylori-negative low-grade gastric MALT lymphoma. World J Gastroenterol 2010; 16(17): 2158-2162

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