May 10, 2010
Dementia Takes Away The Meaning Of Flavors
Flavor is literally the spice of life and for many people life without the pleasures of the table would be unthinkable. Yet just this aspect of everyday life is vulnerable in certain degenerative dementias, with patients developing abnormal eating behaviors including changes in food preferences, faddism and pathological sweet tooth. New research has revealed evidence that these behaviors are linked to a loss of meaning for flavors, as reported in the June 2010 issue of Elsevier's Cortex.
Dr Katherine Piwnica-Worms from Washington University in St Louis, Missouri, together with Dr Jason Warren and colleagues from University College London, investigated the processing of flavor information in patients with semantic dementia, a degenerative disease affecting the temporal lobes of the brain. Patients with this condition suffer a profound loss of the meaning of words and, ultimately, of things in the world at large; in addition, many develop a preference for unusual foods or food combinations.
These findings provide the first evidence that the meaning of flavors, like other things in the world, becomes affected in semantic dementia: this is a truly 'pan-modal' deficiency of knowledge. The research gives clues to the brain basis for the abnormal eating behaviors and the altered valuation of foods shown by many patients with dementia. More broadly, the results offer a perspective on how the brain organizes and evaluates those commonplace flavors that enrich our daily lives.
The article is "Flavor processing in semantic dementia" by Katherine E. Piwnica-Worms, Rohani Omar, Julia C. Hailstone, and Jason D. Warren, and appears in Cortex, Volume 46, Issue 6 (June 2010), published by Elsevier in Italy.
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