Resverlogix Scientific Data Presented at EAS Congress
New data from Phase 1b/2a trial included
TSX Exchange Symbol: RVX
“The data presented in
Resverlogix recently completed a Phase 2 clinical trial called ASSERT to study RVX-208 an oral small molecule therapy for the treatment of atherosclerosis. The ASSERT trial enrolled subjects with stable coronary artery disease. A second planned Phase 2 trial, designated ASSURE, will include subjects with acute coronary syndrome and coronary artery disease of whom all will be examined with intravascular ultrasound (IVUS). Both the ASSERT and ASSURE studies are chaired by Dr.
Cardiovascular disease is the leading cause of death in the US and other developed nations costing the American health care system an estimated
Apolipoprotein A-I (ApoA-I), the main protein component of high-density lipoprotein (HDL), represents the body’s natural defense system against atherosclerosis by mediating reverse cholesterol transport, i.e. transport of peripheral cholesterol including that within the atherosclerotic plaques of the vessel wall to the liver for processing and excretion. In multiple human and animal studies over-expression or repeated infusion of ApoA-I inhibit progression and induce regression of atherosclerosis in animals and humans. Developing small molecules that increase ApoA-I would satisfy a large unmet medical need.
About Resverlogix Corp.
Resverlogix Corp. is a leading biotechnology company engaged in the development of novel therapies for important global medical markets with significant unmet medical needs. The NexVas(TM) PR program is the Company’s primary focus which is to develop novel small molecules that enhance ApoA-I. These vital therapies address the burden of atherosclerosis and other important diseases such as Acute Coronary Syndrome, Diabetes, Alzheimer’s disease, Peripheral Artery Disease and other vascular disorders. Resverlogix Corp.’s common shares trade on the Toronto Stock Exchange (TSX:RVX). For further information please visit www.resverlogix.com.
This news release may contain certain forward-looking statements as defined under applicable Canadian securities legislation, including our statements with respect to, the current and/or future financings, research, development and commercialization of novel therapeutics that reduce the risk of cardiovascular disease including atherosclerosis, diabetes, Alzheimer’s disease, Peripheral Artery Disease and other vascular diseases. These forward-looking statements contained herein that are not based on historical fact, including without limitation statements containing the words “believes”, “anticipates”, “plans”, “intends”, “will”, “should”, “expects”, “continue”, “estimate”, “forecasts” and other similar expressions. Our actual results, events or developments could be materially different from those expressed or implied by these forward-looking statements. We can give no assurance that any of the events or expectations will occur or be realized. By their nature, forward-looking statements are subject to numerous known and unknown risks and uncertainties including but not limited to those associated with the success of research and development programs, clinical trial programs including possible delays in patient recruitment, the regulatory approval process, competition, securing and maintaining corporate alliances, market acceptance of the Company’s products, the availability of government and insurance reimbursements for the Company’s products, the strength of intellectual property, financing capability, the potential dilutive effects of any financing, reliance on subcontractors and key personnel and additional risk factors discussed in other documents we file from time to time with securities authorities, which are available through SEDAR at www.sedar.com. Additionally, risks and uncertainties are discussed in detail in the
SOURCE Resverlogix Corp.