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Studies Seeking Participants

August 18, 2010

A number of resarch studies at Baylor College of Medicine are seeking participants. These studies are important because they help doctors and researchers uncover the disease process and find potential treatment and cures.

A list of BCM research studies can be found at www.bcm.edu/clinicalstudies/. Among the studies listed:

Older men with smoking history needed for bladder cancer screening study

Men over the age of 60 who have smoked for at least 20 years are being asked to participate in a bladder cancer screening study at Baylor College of Medicine.

Currently, there is no established screening method for bladder cancer.

Cancer-causing chemicals in cigarette smoke pass into the urine where they can affect the bladder lining and, over time, cause cellular changes that lead to cancer.

Blood in the urine is one of the first signs that a tumor may be growing in the bladder.

BCM will be one of four institutions involved in the trial, which will recruit 375 participants at BCM and 1,500 patients in the United States and Canada. Other trial sites include The University of Texas MD Anderson Cancer Center, The University of Rochester Medical Center in Rochester, NY and Laval University in Quebec, Canada.

Men who take part will be given at-home test kits that can detect blood in the urine. They will be asked to test their urine for blood for 10 consecutive days.

If the tests are positive for blood, the researchers in this study will look for cancer cells in the urine, using three urine biomarker tests approved by the U.S. Food and Drug Administration.

They may recommend a cystoscopy (examination of the bladder with an instrument called a cystoscope) and/or imaging study of the kidneys as well as follow-up with a urologist to complete the diagnostic evaluation for blood in the urine. Participants may also be asked to take part in a study designed to identify genetic risk factors for bladder cancer.

Those who take part in the study will also be asked about their medical history, other medications and health conditions. Bladder cancer is the fourth most common cancer in men.

The study is being sponsored by the National Institutes of Health.

For more information on enrollment, contact Susan Kingston at 713-798-8514 or slk@bcm.edu.

Volunteers needed for smallpox clinical research study

Baylor College of Medicine is recruiting volunteers for a seven-month smallpox study. Volunteers must be at least 18 years old, born after 1971 and be in general good health.

Volunteers will be asked to take two shots of the smallpox vaccine and follow up with clinic visits and phone calls for approximately seven months.

Volunteers will be compensated for their time. Call 713-798-4912.

Volunteers needed for Latino asthma study

Experts at Baylor College of Medicine are recruiting volunteers for a study that will help to explain why asthma affects Latino ethnic groups differently than other populations.

“Asthma burdens more Puerto Ricans, fewer Dominicans and even fewer Mexicans and Central Americans. We hope to learn why this is the case and what it tells us about the genetic and environmental factors that lead to asthma,” said Dr. Harold Farber, associate professor of pediatrics ““ pulmonary at BCM.

To qualify for the study, participants must:

    * Be between the ages of 8 and 21 years old
    * Not have other severe health problems
    * Be of Latino heritage

Those selected for the study will:

    * Be given a free lung function test
    * Be tested for common allergies
    * Give a blood sample
    * Complete a questionnaire
    * Be asked to return for other tests

The study is recruiting volunteers with and without asthma. Participants will also be compensated for their time. For more information on this study funded by the National Institutes of Health, call Blanca Lopez at 832-822-4252.

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