September 21, 2010
Stopping Nerve Death in ALS
(Ivanhoe Newswire) -- Researchers have found a way to improve the lives of animals with amyotrophic lateral sclerosis (ALS), which is also known as Lou Gehrig's disease.
Investigators from the University of California, San Francisco prevented symptom onset, weight loss, and paralysis in a mouse model of ALS. They were also able to extend lives.
In the study, genetically eliminating activation of the mitochondrial apoptotic pathway preserved nerve cell viability and function, thus helping animals with the disease.
According to the ALS Association, ALS affects more than 5,600 people in the U.S. each year. About 30,000 Americans are living with the disease at any given time.
SOURCE: Journal of Clinical Investigation, September 2010